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Folic Acid Metabolism in Health and Disease
Abstract: This publication provides a background on the biochemistry and physiology of folic acid and discusses recent developments in analytical methodology and the clinical aspects of folic acid nutrition. Topics include: an historical account of the advances in the biochemistry and function of folic acid; the regulation of folic acid metabolism and the use of antagonists to study folate metabolism and transport by cells; the intestinal absorption of dietary folates; microbiological growth techniques; ani mal bioassays for measuring bioavailability of food folates; clinical aspects of dietary, physiological, and deficiency concerns; and the evaluation of folate nutritional status in infants, adolescents, adults, and other population groups.
Folate and disease prevention
This review updates the report by the Committee on Medical Aspects of Food Policy (COMA) "Folic acid and the prevention of disease" (Report on health and social subjects no. 50, 2000, ISBN 0113223048). The Committee has weighed the evidence which shows significant benefits of folic acid fortification in reducing the risk of pregnancies affected by a neural tube defect (NTD) against the evidence of potential harm in fortification in relation to delaying diagnosis of vitamin B12 deficiency and increasing the progression of bowel cancer. It recommends mandatory fortification of flour with folic acid as the most effective way to increase folate intakes of women most at risk of NTD-affected pregnancies, provided voluntary fortification is controlled and advice is given about supplement use. Such a policy is judged to be of net benefit to the UK population as it would lead to a redistribution of folic acid intakes, improving the folate intake of low consumers while reducing the intakes of high consumers.
Functional Food
In recent years, the concern of society about how food influences the health status of people has increased. Consumers are increasingly aware that food can prevent the development of certain diseases, so in recent years, the food industry is developing new, healthier products taking into account aspects such as trans fats, lower caloric intake, less salt, etc. However, there are bioactive compounds that can improve the beneficial effect of these foods and go beyond the nutritional value. This book provides information on impact of bioactive ingredients (vitamins, antioxidants, compounds of the pulses, etc.) on nutrition through food, how functional foods can prevent disease, and tools to evaluate the effects of bioactive ingredients, functional foods, and diet.
Folic Acid
Folic Acid is clearly written in language that is easily understood by the average reader. While solidly based on peer-reviewed research, this book is a very readable, basic primer for anyone who wants the benefits of improved health and longevity. It is our humble opinion that even health professionals could benefit greatly from referring to this absolutely up-to-date summation of all relevant published research through November, 2006. Folic acid is the popular synthetic form, the term folate referes to all members of this vitamin family. Folates are best known for theirimportance in avoiding birth defects, but research in the last few years has established that they are absolutely essentia...
Folate in Health and Disease
During the fifteen years since the bestselling first edition of Folate in Health and Disease was published, there have been thousands of new research studies related to folate and its role in health and disease. The second edition of the book uniquely bridges the gap between basic science and public health/clinical medicine.Presents Groundbreaking
Nutrient Metabolism
Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source.Key Features* Highly illustrated with relevant chemical structures and metabolic pathways* Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry* First comprehensive work on the subject
Folic Acid and Folates
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. *Includes color illustrations *Available on ScienceDirect *Longest running series published by Academic Press *Contributions by leading international authorities
Williams Hematology, 10th Edition
The landmark text that has guided generations of hematologists and related practitioners―updated with the latest research findings and improved format and presentation Long revered for its comprehensiveness and extraordinary depth of detail, Williams Hematology provides essential coverage of the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood and marrow cells and coagulation proteins. The text contains a wealth of basic science and translational pathophysiology for optimal, lifelong learning. Experts in research and clinical hematology, the editors are known worldwide for their contributions to the field. This new edition contains everythin...
