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Mitochondrial Dysfunction
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alteration...
Textbook of Hemophilia
The only up-to-date definitive reference source onhemophilia This book is an invaluable resource that provides an overview ofall aspects of the care of patients with haemophilia. Covering how to assess both bleeding children and adults,Haemophilia A and B, molecular basis of the disease, the role offactors in coagulation, epidemiology, pharmacokinetics, andtreatment of inhibitors. There will also be a section onmusculoskeletal aspects of haemophilia as well as newerdevelopments such as gene therapy and rare bleedingdisorders. Textbook of Hemophilia is ideal for: Trainees and residents in hematology Hematologists in practice Specialists working in thrombosis and hemostasis as well astransfusion medicine Why Buy This Book? The only up-to-date definitive reference source onhemophilia Essential for all those managing hemophilia patients Detailed guidance on assessment, diagnosis, management andtreatment Advice for everyday clinical questions Edited by three of the world’s leading experts onhemophilia
Encyclopedia of Snow, Ice and Glaciers
The earth’s cryosphere, which includes snow, glaciers, ice caps, ice sheets, ice shelves, sea ice, river and lake ice, and permafrost, contains about 75% of the earth’s fresh water. It exists at almost all latitudes, from the tropics to the poles, and plays a vital role in controlling the global climate system. It also provides direct visible evidence of the effect of climate change, and, therefore, requires proper understanding of its complex dynamics. This encyclopedia mainly focuses on the various aspects of snow, ice and glaciers, but also covers other cryospheric branches, and provides up-to-date information and basic concepts on relevant topics. It includes alphabetically arranged ...
Mathematics Education in the Digital Age
The wide availability of digital educational resources for mathematics teaching and learning is indisputable, with some notable genres of technologies having evolved, such as graphing calculators, dynamic graphing, dynamic geometry and data visualization tools. But what does this mean for teachers of mathematics, and how do their roles evolve within this digital landscape? This essential book offers an international perspective to help bridge theory and practice, including coverage of networking theories, curriculum design, task implementation, online resources and assessment. Mathematics Education in the Digital Age details the impacts this digital age has, and will continue to have, on the...
Comics Beyond the Page in Latin America
Comics Beyond the Page in Latin America is a cutting-edge study of the expanding worlds of Latin American comics. Despite lack of funding and institutional support, not since the mid-twentieth century have comics in the region been so dynamic, so diverse and so engaged with pressing social and cultural issues. Comics are being used as essential tools in debates about, for example, digital cultures, gender identities and political disenfranchisement.
The Mechanical Properties of Sea Ice
The review discusses the state of thinking of each of the main national groups investigating sea ice and gives an overall appraisal of the field as a whole. Emphasis is placed on (1) the physical basis for interpreting sea ice strength (phase relations, air volume, and structural considerations), (2) theoretical considerations (strength models, air bubbles and salt reinforcement, and interrelations between growth conditions and strength), (3) experimental results (tensile, flexural, shear, and compressive strength, elastic modulus, shear modulus and Poisson's ratio, time dependent effects, and creep), and (4) plate characteristics. The paper includes a review of problems in sea ice investigations, relates the chemical, crystallographic, mechanical, and physical aspects involved, and concludes by showing how to utilize this knowledge to solve practical problems. (Author).
Animal Models of Acute Neurological Injuries
Despite numerous recent studies and exciting discoveries in the field, only limited treatment is available today for the victims of acute neurological injuries. Animal Models of Acute Neurological Injuries provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that currently jeopardizes advances in the field. Contributed by top experts and many original developers of the models, each chapter contains a step-by-step, proven procedure and visual aids covering the most commonly used animal models of neurological injury in order to highlight the practical applications of animal models rather than the theoretical issues. This intensive volume presents its readily reproducible protocols with great clarity and consistency to best aid neuroscientists and neurobiologists in laboratory testing and experimentation. Comprehensive and cutting-edge, Animal Models of Acute Neurological Injuries is an ideal guide for scientists and researchers who wish to pursue this vital course of study with the proficiency and precision that the field requires.
