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The Learned King
This book is a volume in the Penn Press Anniversary Collection. To mark its 125th anniversary in 2015, the University of Pennsylvania Press rereleased more than 1,100 titles from Penn Press's distinguished backlist from 1899-1999 that had fallen out of print. Spanning an entire century, the Anniversary Collection offers peer-reviewed scholarship in a wide range of subject areas.
The Gibraltar Crusade
The epic battle for control of the Strait of Gibraltar waged by Castile, Morocco, and Granada in the late thirteenth and early fourteenth centuries is a major, but often overlooked, chapter in the history of the Christian reconquest of Spain. After the Castilian conquest of Seville in 1248 and the submission of the Muslim kingdom of Granada as a vassal state, the Moors no longer loomed as a threat and the reconquest seemed to be over. Still, in the following century, the Castilian kings, prompted by ideology and strategy, attempted to dominate the Strait. As self-proclaimed heirs of the Visigoths, they aspired not only to reconstitute the Visigothic kingdom by expelling the Muslims from Spai...
Enemies in the Plaza
Toward the end of the fifteenth century, Spanish Christians near the border of Castile and Muslim-ruled Granada held complex views about religious tolerance. People living in frontier cities bore much of the cost of war against Granada and faced the greatest risk of retaliation, but had to reconcile an ideology of holy war with the genuine admiration many felt for individual members of other religious groups. After a century of near-continuous truces, a series of political transformations in Castile—including those brought about by the civil wars of Enrique IV's reign, the final war with Granada, and Fernando and Isabel's efforts to reestablish royal authority—incited a broad reaction ag...
The Last Crusade in the West
By the middle of the fourteenth century, Christian control of the Iberian Peninsula extended to the borders of the emirate of Granada, whose Muslim rulers acknowledged Castilian suzerainty. No longer threatened by Moroccan incursions, the kings of Castile were diverted from completing the Reconquest by civil war and conflicts with neighboring Christian kings. Mindful, however, of their traditional goal of recovering lands formerly ruled by the Visigoths, whose heirs they claimed to be, the Castilian monarchs continued intermittently to assault Granada until the late fifteenth century. Matters changed thereafter, when Fernando and Isabel launched a decade-long effort to subjugate Granada. Uti...
The Art of Conversion
Art of Conversion: Christian Visual Culture in the Kingdom of Kongo
Iron as Therapeutic Targets in Human Diseases
Iron is an essential element for almost all organisms, a cofactor playing a crucial role in a number of vital functions, including oxygen transport, DNA synthesis, and respiration. However, its ability to exchange electrons renders excess iron potentially toxic, since it is capable of catalyzing the formation of highly poisonous free radicals. As a consequence, iron homeostasis is tightly controlled by sophisticated mechanisms that have been partially elucidated. Because of its biological importance, numerous disorders have been recently linked to the deregulation of iron homeostasis, which include not only the typical disorders of iron overload and deficiency but also cancer and neurodegene...
Clinical Significance of C-reactive Protein
This book explores the latest developments in the field the acute phase protein (APP), C-reactive protein or CRP in different diseases, highlighting the structural and functional aspects of CRP in disease biology. Divided into 5 sections, the book examines important topics such as the role of CRP in neurodegenerative, cardiac and parasitic diseases, as well as in cancer and inflammatory bowel disease, and the expression of CRP in pediatric respiratory diseases. In addition it discusses the clinical role of CRP in diagnostics and therapeutics, sepsis, ICU and ITU patients, and also as a primary marker for inflammation. Given its scope, this book will appeal to scholars in various fields of medicine and biology.
