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Clinical Blood Pool MR Imaging
  • Language: en
  • Pages: 263

Clinical Blood Pool MR Imaging

Magnetic resonance angiography has made great strides, with continuing improvements in hardware, pulse sequencing, and know-how allowing ever-increasing speed, resolution, and suppression of artifacts. However, an inherent physical barrier has always been limited SNR. Gadolinium contrast agents help to increase SNR by facilitating T1 relaxation, but they can be injected only at a finite rate and at a limited molar dose, and there is a rapid drop in c- centration following the brief arterial phase due to redistribution into the extracellular fluid compartment. With its sixfold increase in T1 relaxivity, blood pool distribution, and longer serum half-life, Vasovist® represents a new breakthro...

Fibroblast Activation Protein Imaging, An Issue of PET Clinics, E-Book
  • Language: en
  • Pages: 177

Fibroblast Activation Protein Imaging, An Issue of PET Clinics, E-Book

In this issue, guest editors bring their considerable expertise to this important topic. Contains 16 practice-oriented topics including fibroblast activation protein inhibitor (FAPI) PET imaging in pancreatic cancer; fibroblast activation protein inhibitor (FAPI) PET imaging in colorectal cancer; fibroblast activation protein inhibitor (FAPI) cardiac imaging; fibroblast activation protein inhibitor (FAPI) PET/CT in gastric cancer; and more. Provides in-depth clinical reviews on fibroblast activation protein imaging, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Medical Imaging in Clinical Trials
  • Language: en
  • Pages: 422

Medical Imaging in Clinical Trials

In the last few years the use of medical imaging has increased exponentially in routine clinical practice. This has been reflected in a rapidly increasing use of medical imaging in clinical trials, through all phases. More recently this has culminated in a number of inter-disciplinary meetings with the various stake holders, including the FDA. Changes in the regulatory process has resulted, when it comes to the submission of data to the FDA, in a therapeutic agent where one or more of the trial end-points is the assessment of a radiological end-point. No longer is it sufficient to have the images read by the local investigator site. The FDA has also identified Medical Imaging as one of the k...

PET/MRI in Oncology
  • Language: en
  • Pages: 435

PET/MRI in Oncology

  • Type: Book
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  • Published: 2018-01-23
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  • Publisher: Springer

In this book, experts from premier institutions across the world with extensive experience in the field clearly and succinctly describe the current and anticipated uses of PET/MRI in oncology. The book also includes detailed presentations of the MRI and PET technologies as they apply to the combined PET/MRI scanners. The applications of PET/MRI in a wide range of oncological settings are well documented, highlighting characteristic findings, advantages of this dual-modality technique, and pitfalls. Whole-body PET/MRI applications and pediatric oncology are discussed separately. In addition, information is provided on PET technology designs and MR hardware for PET/MRI, MR pulse sequences and contrast agents, attenuation and motion correction, the reliability of standardized uptake value measurements, and safety considerations. The balanced presentation of clinical topics and technical aspects will ensure that the book is of wide appeal. It will serve as a reference for specialists in nuclear medicine and radiology and oncologists and will also be of interest for residents in these fields and technologists.

Diagnostic Techniques and Surgical Management of Brain Tumors
  • Language: en
  • Pages: 548

Diagnostic Techniques and Surgical Management of Brain Tumors

The focus of the book Diagnostic Techniques and Surgical Management of Brain Tumors is on describing the established and newly-arising techniques to diagnose central nervous system tumors, with a special focus on neuroimaging, followed by a discussion on the neurosurgical guidelines and techniques to manage and treat this disease. Each chapter in the Diagnostic Techniques and Surgical Management of Brain Tumors is authored by international experts with extensive experience in the areas covered.

Tumors of the Central Nervous System, Volume 11
  • Language: en
  • Pages: 396

Tumors of the Central Nervous System, Volume 11

Like the ten preceding volumes in the series Tumors of the Central Nervous System, this book is distinguished for its comprehensive approach, its distinguished roster of some 93 contributors representing 8 different countries and its embrace of leading-edge technology and methods. Volume 11: Imaging, Glioma and Glioblastoma, Stereotactic Radiotherapy, Spinal Cord Tumors, Meningioma, and Schwannomas concentrates on the diagnosis, prognosis and therapy of four types of tumors, namely Glioblastoma, Meningioma, Schwannoma and Spinal Tumors. The book offers an in-depth survey of a range of new technologies and their applications to tumor diagnosis, treatment and therapy assessment. The contributors explain in thorough detail a range of current and newly developed imaging methods, including molecular imaging and PET scan. Also covered is molecular profiling of brain tumors to select therapy in clinical trials of brain tumors. Discussion includes a review of such surgical treatments as resection and the application of non-invasive stereotactic radiosurgery for treating high-risk patients with brain metastasis. Additional discussion is devoted to tumor seeding.

Molecular Imaging in Oncology
  • Language: en
  • Pages: 911

Molecular Imaging in Oncology

This book discusses the most significant recent advances in oncological molecular imaging, covering the full spectrum from basic and preclinical research to clinical practice. The content is divided into five sections, the first of which is devoted to standardized and emerging technologies and probe designs for different modalities, such as PET, SPECT, optical and optoacoustic imaging, ultrasound, CT, and MRI. The second section focuses on multiscale preclinical applications ranging from advanced microscopy and mass spectroscopy to whole-body imaging. In the third section, various clinical applications are presented, including image-guided surgery and the radiomic analysis of multiple imaging features. The final two sections are dedicated to the emerging, crucial role that molecular imaging can play in the planning and monitoring of external and internal radiotherapy, and to future challenges and prospects in multimodality imaging. Given its scope, the handbook will benefit all readers who are interested in the revolution in diagnostic and therapeutic oncology that is now being brought about by molecular imaging.

Prostate Cancer, An Issue of PET Clinics, E-Book
  • Language: en
  • Pages: 121

Prostate Cancer, An Issue of PET Clinics, E-Book

In this issue of PET Clinics, guest editors Drs. Harshad R. Kulkarni and Abass Alavi bring their considerable expertise to the topic of Prostate Cancer. PET imaging for prostate cancer continues to evolve as new radiotracers and imaging modalities are combined. This issue offers an up-to-date review of the most popular radiotracers and how PET imaging is combined with MR, CT, and ultrasound to provide the most accurate diagnosis of prostate cancer. Contains 12 practice-oriented topics including the role of ultrasound, CT, and MRI in managing patients with prostate cancer; Ga68 PSMA imaging; PET imaging for prostate cancer using F-18 Fluciclovine; PET imaging for prostate cancer using Ga-68 RM2; the role of NaF PET in the imaging of prostate cancer; and more. Provides in-depth clinical reviews on prostate cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Gastrointestinal Oncology
  • Language: en
  • Pages: 645

Gastrointestinal Oncology

GASTROINTESTINAL ONCOLOGY Blends quality research findings with advanced educational techniques in a uniquely comprehensive approach Written and edited by leading international experts in the field, Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach is an indispensable reference for clinicians, medical practitioners, and trainees involved in the investigation, diagnosis, and treatment of esophageal, gastric, intestinal, colonic, hepatobiliary, pancreatic, and other gastrointestinal tumors. Drawing on the most current evidence-based knowledge, this comprehensive resource reflects the current care of GI cancer patients, enabling effective clinical decision making and patient...

Neuroendocrine Neoplasms, An Issue of PET Clinics, E-Book
  • Language: en
  • Pages: 145

Neuroendocrine Neoplasms, An Issue of PET Clinics, E-Book

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize