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Pathogenesis of Periodontal Diseases
This book aims to provide clinicians with a refined understanding of the biology that underlies periodontal diseases, thereby offering a sound basis for improved clinical decision making with regard to prevention strategies, diagnosis, and therapy. All significant aspects of periodontal pathogenesis are covered, including the roles played by the oral microbiome and biofilms, bacterial virulence factors, cells of the immune system, matrix metalloproteinases, proinflammatory and osteolytic cytokines, genetic factors, and antimicrobial peptides. Periodontal diseases are among the most common infectious diseases in humans, and the primary cause of tooth loss in adults. The functional and esthetic problems associated with these diseases compromise quality of life, and their treatment imposes large financial burdens on national health systems and private patients. Up-to-date knowledge of periodontal pathogenesis is therefore essential for the contemporary clinician. This book, written by experts from Europe and the Americas, delivers such knowledge in an accessible, clinician-friendly way.
Oral Mucosal Immunity and Microbiome
The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems. In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk.
Periodontitis
Periodontitis is an infection-induced inflammatory disease accounting for huge healthcare costs and socio-economic impacts. Bacteria from the indigenous oral flora colonize the interspace between the tooth and the connective tissue, which induces an inflammatory response. If the bacteria proliferate and release virulence factors, they cause an imbalance in the host inflammatory response that induces degenerative processes in the surrounding tissues. This process is often slow, and the disease affects mainly older people, but the process could be rapid and affect young individuals if certain pathogens colonize the area. The two most studied periodontal pathogens, Porphyromonas gingivalis and ...
Biomaterials Associated Infection
With BAI being one of the most common complications associated with implantation of any biomaterial, this vital book features contributions from leaders in the field who address this critical problem in applying biomaterials research to clinical practice.
Practical Periodontics - E-Book
The second edition of this popular textbook provides a concise and easy-to-follow guide that will increase the confidence of students and clinicians alike in managing all aspects of periodontal care. Practical Periodontics provides evidence-based information on the essentials of clinical periodontology, written by internationally renowned contributors in an accessible, practical style. It covers all aspects of the discipline, including the aetiology of periodontal diseases, clinical management, patient education, paediatric care, and the interaction of periodontology with other dental disciplines such as implant dentistry and orthodontics. This book will be invaluable to all undergraduate de...
Debonding and Fixed Retention in Orthodontics
Debonding and Fixed Retention in Orthodontics An accessible and thorough guide to debonding and fixed retainer bonding Debonding and Fixed Retention in Orthodontics: An Evidence-Based Clinical Guide reviews the protocols, materials, and techniques required at two key stages of orthodontic treatment. The book has been written as a reference guide and the chapters introduce the best-supported and most efficient approaches to each stage of debonding and fixed retainer bonding treatments, from choice of material through to final results. The book includes relevant procedures including orthodontic appliance removal, appliance debonding, the use of rotating instruments, and enamel cleaning. The au...
Aggregatibacter actinomycetemcomitans—Gram-Negative Bacterial Pathogen
Aggregatibacter actinomycetemcomitans is a well-studied Gram-negative bacterium that can often be found in the oral cavity of young individuals. It has several virulence factors and a large genetic diversity, which results in both harmless and highly virulent genotypes. To determine the virulence potential of the isolated bacteria, genetic profiling is recommended. Advanced knowledge of the virulence mechanisms induced by this bacterium is important for the development of future personalized preventive and treatment strategies. The fifteen papers in this book provide a strong and relevant background that can contribute to the improvement of future diagnosis and research strategies.
Dental Implants and Oral Microbiome Dysbiosis
This book will serve as a one-stop, reference manual to understand the basic concepts of dental implant design, the related microbiome, research models and current concepts as well as futuristic perspectives in implant surface modification. The manual-like design including colorful illustrations and important critical questions will help researchers and advanced students in understanding the contemporary status and in designing studies for innovative treatments of dental implant infections. Considering the microbiome of dental implant related environment in health and disease is imperative to design strategies to good practice and prevention of infections around implants. This monograph will serve as a single reference material which links the interdisciplinary aspect of the dental implants covering material sciences, engineering and biological aspects, thus effectively bridging the gap between engineering and oral health sciences.
Use of Saliva in Diagnosis of Periodontitis: Cumulative Use of Bacterial and Host-Derived Biomarkers
Periodontitis is an infection-induced inflammatory disease of the tooth supporting tissues. Treatment of periodontal diseases and regeneration of the effected tissues can be possible only in the early diagnosis of the disease. If left undiagnosed or untreated, periodontitis leads to irreversible soft and hard tissue destruction and finally to tooth loss. Saliva is known to contain inflammatory mediators, host tissue and cell degradation products as well as microbial metabolites and enzymes, reflecting the health status of the oral cavity. In this topic, in collaboration with the well-known scientists working on the field of salivary diagnostics, we demonstrate evidence on monitoring periodontitis by salivary analysis.
