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The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprin...
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Enormous advances in our knowledge of genetic contributions to aging and disease, and in our understanding of the potential for manipulation of the aging process, have taken place during the past 20 years. This is the first volume in decades to consolidate this research in one place. It provides a broad and current overview of the most promising advances in genetic research on aging, current understanding of genetic contributions to the basic processes of aging, and age-related disease. The Review focuses on the aging process from lower organisms to man, and is organized in ascending order of biological complexity starting with stem cells and progressing through worms, flies, mice, and human...
The gold-standard text on the diagnosis and treatment of disorders affecting the elderly – completely updated with a new full-color presentation A Doody's Core Title for 2021! The definitive treatise on the subject of geriatrics, this comprehensive text combines gerontology principles with clinical geriatrics, offering a uniquely holistic approach to this ever-expanding area of medicine. Written by some of the world’s most respected geriatricians, Hazzard’s Geriatric Medicine and Gerontology, Seventh Edition presents up-to-date, evidence-based information in a rich new full-color design. Unmatched as a textbook, this classic is also valuable to fellows in geriatric medicine. Hazzards...
First Enoch is an ancient Judean work that inaugurated the genre of apocalypse. Chapters 1-36 tell the story of the descent of angels called "Watchers" from heaven to earth to marry human women before the time of the flood, the chaos that ensued, and God's response. They also relate the journeying of the righteous scribe Enoch through the cosmos, guided by angels. Heaven, including the place and those who dwell there (God, the angels, and Enoch), plays a central role in the narrative. But how should heaven be understood? Existing scholarship, which presupposes "Judaism" as the appropriate framework, views the Enochic heaven as reflecting the temple in Jerusalem, with God's house replicating ...
Death rears its ugly head everywhere and at all times, in all sorts of situations and under many kinds of circumstances and for a myriad of reasons, affecting people in surprising ways, but eventually coming for everyone no matter their station in life. But why do we find their demises encoded in the Five Books of Moses? What is it about a sacred text of 304,805 Hebrew letters that enables it to hold the whole history of humankind and encoded within it the specific circumstances under which particular people have died or are going to die? Connected to the types of events listed in this book are found the names of those who died in instances of those particular events, except in part 6 where ...
The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprin...
There is a sickness at the heart of left-wing British politics, and though predominantly below the surface, it is silently spreading, becoming ever more malignant. With three separate inquiries into anti-Semitism in the Labour Party in the first six months of 2016 alone, it seems hard to believe that, until the 1980s, the British left was broadly pro-Israel. And while the election of Jeremy Corbyn may have thrown a harsher spotlight on the crisis, it is by no means a recent phenomenon. The widening gulf between British Jews and the anti-Israel left - born out of antiapartheid campaigns and now allying itself with Islamist extremists who demand Israel's destruction - did not happen overnight or by chance: political activists made it happen. This book reveals who they were, why they chose Palestine and how they sold their cause to the left. Based on new academic research into the origins of this phenomenon, combined with the author's daily work observing political extremism, contemporary hostility to Israel, and anti-Semitism, this book brings new insight to the left's increasingly controversial 'Jewish problem'.
Jews and Science examines the complicated relationship between Jewish identities and the evolving meanings of science throughout the history of Western academic culture. Jews have been not only the agents for study of things Jewish, but also the subject of examination by “scientists” across a range of disciplines, from biology and bioethics to anthropology and genetics. Even the most recent iteration of Jewish studies as an academic discipline—Israel studies—stresses the global cultural, economic, and social impact of Israeli science and medicine. The 2022 volume of the Casden Institute’s Jewish Role in American Life series tackles a range of issues that have evolved with the rise ...
A New York Times Notable Book of 2014 We are doomed to repeat history if we fail to learn from it, but how are we affected by the forces that are invisible to us? What role does Neanderthal DNA play in our genetic makeup? How did the theory of eugenics embraced by Nazi Germany first develop? How is trust passed down in Africa, and silence inherited in Tasmania? How are private companies like Ancestry.com uncovering, preserving and potentially editing the past? In The Invisible History of the Human Race, Christine Kenneally reveals that, remarkably, it is not only our biological history that is coded in our DNA, but also our social history. She breaks down myths of determinism and draws on cutting - edge research to explore how both historical artefacts and our DNA tell us where we have come from and where we may be going.