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The Global Antimicrobial Resistance Epidemic
Antibiotic resistance is a global health crisis. Misuse of antibiotics in humans, animals, food, and agriculture has compounded the situation. Bacterial infections have returned decades after medicines were first used. This book discusses antibiotic resistance and some of the organisms that pose immediate, serious, and alarming dangers. It highlights the need for a broader, more comprehensive approach to fighting bacterial infections, which may involve non-compound techniques (other than standard antibacterial drugs) that target bacteria or the host, such as antibodies, probiotics, phytobiotics, and vaccinations.
Environmental Pollution of Paddy Soils
The paddy field is a unique agro-ecosystem and provides services such as food, nutrient recycling and diverse habitats. However, chemical contamination of paddy soils has degraded the quality of this important ecosystem. This book provides an overview of our current understanding of paddy soil pollution, addressing topics such as the major types of pollutants in contaminated paddy soil ecosystems; factors affecting the fate of pollutants in paddy soil; biomonitoring approaches to assess the contaminated paddy soil; the impact of chemicals on soil microbial diversity; and climate change. It also covers arsenic and heavy metal pollution of paddy soils and their impact on rice quality. Further, new emerging contaminants such as antibiotics and antibiotics resistance genes (ARGs) in paddy soil and their impact on environmental health are also discussed. The last chapters focus on the bioremediation approaches for the management of paddy soils.
Practical Applications of Computational Biology & Bioinformatics, 14th International Conference (PACBB 2020)
This book highlights the latest research on practical applications of computational biology and bioinformatics, and addresses emerging experimental and sequencing techniques that are posing new challenges for bioinformatics and computational biology. Successfully applying these techniques calls for new algorithms and approaches from fields such as statistics, data mining, machine learning, optimization, computer science, and artificial intelligence. In response to these challenges, we have seen the rise of a new generation of interdisciplinary scientists with a strong background in the biological and computational sciences.These proceedings include 21 papers covering many different subfields of bioinformatics and computational biology. Focusing on interdisciplinary applications that combine e.g. bioinformatics, chemoinformatics, and system biology, they are intended to promote the collaboration of scientists from different research groups and with different backgrounds (computer scientists, mathematicians, biologists) to reach breakthrough solutions and overcome the challenges outlined above.
Integrated approaches to health
One Health addresses health challenges arising from the intertwined spheres of humans, animals and ecosystems. This handbook is the product of an interdisciplinary effort to provide science-based guidance for the evaluation of One Health and other integrated approaches to health. It guides the reader through a systems approach and framework to evaluate such approaches in a standardised way. It provides an overview of concepts and metrics from health and life sciences, social sciences, economics, and ecology that are relevant for the evaluation of the processes involved, as well as the characterisation of expected and unexpected outcomes of One Health initiatives. Finally, the handbook provides guidance and practical protocols to help plan and implement evaluations in order to generate new insights and provide meaningful information about the value of One Health. The handbook is intended for practitioners, researchers, evaluators as well as funders of integrated approaches to health and beyond.
Salmonella
The discovery of Salmonella in swine in 1885 marked the beginning of intense efforts to control salmonellae that have continued for the past 127 years. The majority of foodborne outbreaks are caused by only a few of the 2500+ known serovars. While progress has been made on many fronts, salmonellosis has yet to be eliminated in either developed or in developing nations. This work represents the collective contributions of authors from all around the world. Chapters in this book address a wide array of topics related to understanding and controlling this pathogen, including: Salmonella as studied in the environment, air and in food products; virulence and pathogenicity; control by bacteriophages and other antimicrobials; bacterial adaptation; etc.
Antibiotics and Antimicrobial Resistance Genes
This volume summarizes and updates information about antibiotics and antimicrobial resistance (AMR)/antibiotic resistant genes (ARG) production, including their entry routes in soil, air, water and sediment, their use in hospital and associated waste, global and temporal trends in use and spread of antibiotics, AMR and ARG. Antimicrobial/antibiotic resistance genes due to manure and agricultural waste applications, bioavailability, biomonitoring, and their Epidemiological, ecological and public health effects. The book addresses the antibiotic and AMR/ARG risk assessment and treatment technologies, for managing antibiotics and AMR/ARG impacted environments The book's expert contributions spa...
Rational Design of Multi-Functional Nanomaterials
One of the most important issues, when a nanomaterial is designed, is to control the synthetic pathways to ensure the final desired product. A combination of dry and wet procedures, as well as chemical and physical methodologies, it is possible to successfully prepare new multifunctional nanomaterials, often as a result of multidisciplinary cooperation between chemists, physics, biologist, physicians, material engineers, etc. Drug delivery, environmental detection of contaminants, and many industrial applications directly rely on properties such as water solubility, permeability, cell penetration, shape control, and size of the monodispersed nanoparticle, among others. Functionalized nanomat...
Emerging Modalities in Mitigation of Antimicrobial Resistance
Antimicrobial resistance (AMR) is one of the deadliest threats to global public health. This book focuses on dynamics in the landscape of AMR while informing about the latest technologies and strategies to mitigate it. The menace of AMR in different niches, routes of penetration across various domains, socio-economic impact, and the need for a 'One Health' approach in mitigating AMR has been emphasized. Factors involved in AMR, underlying mechanisms, and pharmacometrics in developing antimicrobials are highlighted. Emphasis is given to emerging technologies that are sustainable, scalable, and applicable to the global community, such as big data analytics, bioactive agents, phage therapy, and nanotechnology. The book also explores current and alternative treatment strategies to combat AMR, emphasizing the use of nanoparticles to target pathogens and as a viable alternative to antibiotics.
