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Novel biomarkers in tumor immunity and immunotherapy
Immune checkpoint inhibitors (ICIs) such as anti-PD-1 and anti-PD-L1 antibodies are highly effective against many types of cancer, yet durable responses are limited to a subset of patients highlighting the need for the development of effective biomarkers to predict prognosis and efficacy. Currently, PD-L1 expression in tumors, microsatellite instability (MSI) or mismatch repair deficiency (dMMR), and tumor mutation burden (TMB) are known as biomarkers for cancer immunotherapy but are not sufficient. Combination therapy with immune checkpoint inhibitors and chemotherapy or radiation therapy, as well as diverse therapies targeting intra-tumoral regulatory T cells have been described, but there...
Tales from a Robotic World
Stories from the future of intelligent machines—from rescue drones to robot spouses—and accounts of cutting-edge research that could make it all possible. Tech prognosticators promised us robots—autonomous humanoids that could carry out any number of tasks. Instead, we have robot vacuum cleaners. But, as Dario Floreano and Nicola Nosengo report, advances in robotics could bring those rosy predictions closer to reality. A new generation of robots, directly inspired by the intelligence and bodies of living organisms, will be able not only to process data but to interact physically with humans and the environment. In this book, Floreano, a roboticist, and Nosengo, a science writer, bring ...
Weaving Fire into Form
This book investigates multiple facets of the emerging discipline of Tangible, Embodied, and Embedded Interaction (TEI). This is a story of atoms and bits. We explore the interweaving of the physical and digital, toward understanding some of their wildly varying hybrid forms and behaviors. Spanning conceptual, philosophical, cognitive, design, and technical aspects of interaction, this book charts both history and aspirations for the future of TEI. We examine and celebrate diverse trailblazing works, and provide wide-ranging conceptual and pragmatic tools toward weaving the animating fires of computation and technology into evocative tangible forms. We also chart a path forward for TEI engagement with broader societal and sustainability challenges that will profoundly (re)shape our children’s and grandchildren’s futures. We invite you all to join this quest.
Distributed, Ambient and Pervasive Interactions
This book constitutes the refereed proceedings of the 5th International Conference on Distributed, Ambient and Pervasive Interactions, DAPI 2017, held as part of the 19th International Conference on Human-Computer Interaction, HCII 2017, held in Vancouver, BC, Canada, in July 2017. The total of 1228 papers presented at the 15 colocated HCII 2017 conferences was carefully reviewed and selected from 4340 submissions. These papers address the latest research and development efforts and highlight the human aspects of design and use of computing systems. The papers accepted for presentation thoroughly cover the entire field of human-computer interaction, addressing major advances in knowledge and effective use of computers in a variety of application areas. This volume contains papers addressing the following major topics: designing and evaluating distributed, ambient and pervasive interactions; natural interaction; smart cities; art and cultural heritage in smart environments; smart environments for quality of life; smart environments for learning and creativity; and ambient games and humour.
Non-Invasive Health Systems based on Advanced Biomedical Signal and Image Processing
This book contains up-to-date noninvasive monitoring and diagnosing systems closely developed by a set of scientists, engineers, and physicians. The chapters are the results of different biomedical projects and theoretical studies that were coupled by simulations and real-world data. Non-Invasive Health Systems based on Advanced Biomedical Signal and Image Processing provides a multifaceted view of various biomedical and clinical approaches to health monitoring systems. The authors introduce advanced signal- and image-processing techniques as well as other noninvasive monitoring and diagnostic systems such as inertial sensors in wearable devices and novel algorithm-based hybrid learning syst...
Things Fall Together
"A short, provocative manifesto for the programmable materials revolution from the visionary founder of MIT's Self-Assembly Lab"--
GPS
This, the second edition of the hugely practical reference and handbook describes kinematic, static and dynamic Global Positioning System theory and applications. It is primarily based upon source-code descriptions of the KSGSoft program developed by the author and his colleagues and used in the AGMASCO project of the EU. This is the first book to report the unified GPS data processing method and algorithm that uses equations for selectively eliminated equivalent observations.
2021 6th International Conference on Intelligent Transportation Engineering (ICITE 2021)
This book features high-quality, peer-reviewed papers from the 2021 6th International Conference on Intelligent Transportation Engineering (ICITE 2021), held in Beijing, China, on October 29–31, 2021. Presenting the latest developments and technical solutions in Intelligent Transportation engineering, it covers a variety of topics, such as intelligent transportation, traffic control, road networking, intelligent automobile and vehicle operation & management. The book will be a valuable reference for graduate and postgraduate audiences, researchers and engineers, working in Intelligent Transportation Engineering.
