Hanna Brucker

Tuning the 3D Microenvironment of Reprogrammed Tubule Cells Enhances Biomimetic Modeling of Polycystic Kidney Disease

• Author(s): Roman Pichler, Ludovica Rizzo, Kevin Tröndle, Michaela Bühler, Hanna Brucker, Anna-Lena Müller, Kelli Grand, Silvia Farè, Amandine Viau, Michael Kaminski, Ernst Wolfgang Kühn, Fritz Koch, Stefan Zimmermann, Peter Koltay, Soeren Lienkamp

• Type: Book
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• Published: 2022
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• Publisher: Unknown

Abstract: Renal tubular cells frequently lose differentiation markers and physiological properties when propagated in conventional cell culture conditions. Embedding cells in 3D microenvironments or controlling their 3D assembly by bioprinting can enhance their physiological properties, which is beneficial for modeling diseases in vitro. A potential cellular source for modeling renal tubular physiology and kidney diseases in vitro are directly reprogrammed induced renal tubular epithelial cells (iRECs). iRECs were cultured in various biomaterials and as bioprinted tubular structures. They showed high compatibility with the embedding substrates and dispensing methods. The morphology of multic...

In re Apportionment of State Legislature-1965-1966; Badgley v. Secretary of State, 377 MICH 396 (1966)

• Type: Book
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• Published: 1966
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• Publisher: Unknown

50999

North western reporter. Second series. N.W. 2d. Cases argued and determined in the courts of Iowa, Michigan, Minnesota, Nebraska, North Dakota, South Dakota, Wisconsin

• Type: Book
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• Published: 1964
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• Publisher: Unknown

None

Regensburger Wochenblatt

• Author(s): Regensburg

• Type: Book
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• Published: 1822
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• Publisher: Unknown

None

Hearings

• Author(s): United States. Congress. House. Committee on Merchant Marine and Fisheries

• Type: Book
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• Published: 1970
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• Publisher: Unknown

None