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This book introduces undergraduate, postgraduate and research students and scientists to animal models of neurological disorders, along with their working principle and brief procedures. Addressing all the disorders related to the central nervous system (CNS) in a single platform, on the basis of various literature surveys it describes different procedures to induce a single disease with the help of toxins/chemicals. It also includes numerous protocols for inducing single neurological diseases, thus fulfilling an urgent need for a book that makes specific procedures for neurological disorders available, so that specific disease can be induced in laboratories according to the availability of resources. Further, it acquaints readers with the pathological changes that occur in a particular neurological disorder, which reflect specific signs and symptoms of any particular disease, and examines how they affect everyday life. It is a valuable resource for researchers aiming to eradicate or improve neurological disorders by testing the benefits of different drugs.
Over the last few decades, various techniques have been developed to alter the properties of plants and animals. While the targeted transfer of recombinant DNA into crop plants remains a valuable tool to achieve a desirable breeding outcome, integration of transgenes into the host genome has been random, which in part, leads to reduced acceptance of GMOs by the general population in some parts of the world. Likewise, methods of induced mutagenesis, such as TILLING, have the disadvantage that many mutations are induced per plant, which has to be removed again by expensive backcrossing. Advances in genome sequencing have provided more and more information on differences between susceptible and...
This book presents best selected papers presented at the International Conference on Paradigms of Computing, Communication and Data Sciences (PCCDS 2020), organized by National Institute of Technology, Kurukshetra, India, during 1–3 May 2020. It discusses high-quality and cutting-edge research in the areas of advanced computing, communications and data science techniques. The book is a collection of latest research articles in computation algorithm, communication and data sciences, intertwined with each other for efficiency.
This fully updated edition provides a series of methods for how best to assess functions of histone deacetylases and acetyltransferases. The disease-relevance of dysregulated protein deacetylation by overexpressed or aberrantly activated histone deacetylases has spurred an intense search for novel and improved inhibitors of these enzymes, as reflected in this collection. Expert contributors explore the generation and evaluation of novel histone deacetylase inhibitors and new and improved techniques to assess acetylation-dependent molecular mechanisms in vitro and in vivo. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols, Second Edition serves as an ideal guide for researchers seeking to further elucidate this vital area of study.
Illustrated Pediatric Dentistry is intended to be a guide to undergraduate and postgraduate students in their understanding of pediatric dentistry. This textbook is modernized with the latest information and techniques in pediatric dentistry. The chapters cover primary pediatric dentistry, its clinical aspects, preventive dentistry, and information about the latest trends in the specialty. The text will equip readers with the knowledge suited to the changing environment of this vital domain. This textbook's editor has over forty-four years of teaching experience in pediatric dentistry and gives their broad perspective through the book content. This book is also the amalgamation of the though...
This book on 3D printing in oral health science aims to equip the reader with a sound understanding of contemporary clinical applications in all fields of dentistry and their future directions. In the last few years, the development of 3D printing for medical and dental applications has increased tremendously. Advancements in 3D printing create the possibility of customized products, savings on small-scale productions, ease of sharing and processing of patient image data, and educational up-gradation. Looking at the dental specialties, it is evident that 3D printing has applications in all aspects of oral health science including prosthodontics, oral surgery, periodontics, endodontics, and orthodontics. This book will cover all major fields in dentistry and will help the practitioner in the process of decision-making and apply concepts in clinical or laboratory practice. It is based on current scientific evidence to provide readers with an up-to-date contemporary understanding of the subject, both from the clinical and the technological side. The book is a valuable asset for all who specialize in 3D printing and for those interested in learning more about this field.
In the current scenario, marked by a continual improvement in living standards, it becomes imperative to boost the productivity as well as the efficiency of agriculture, especially horticulture, which holds the potential for significant economic prosperity aligning with Sustainable Development Goal number 8, "Decent Work and Economic Growth". Modern technological interventions, such as geospatial technology and geographic information system (GIS) technology, can be harnessed to yield effective results in addressing challenges and providing enhanced decision support, particularly in the planning of horticultural resource management. Cultivation and production of fresh produce face several cha...
DARKNESS: PATH OF ILLUMINATION is a collection of poems, quotes and stories by a team of some best writers from all over the country. This book is unique with its content as it consists of some best write-ups covering nearly all the genres that means for a ready it is a complete package as it can be your best friend while travelling too. The main reason behind the Publication of this book is to create love and awareness towards literature in our new generation and to provide a platform for young and emerging writers to showcase their talent. -WVPCUME
“There are instances when the truth suddenly pitches at us with an undeniable impact. Our buried feelings come to the fore due to a trigger in our environment.” What happens when the skeins of life of 16 diverse Indian women, aged 25 to 67, get entwined when they travel to Spain and Portugal in an all-women’s tour? With a galaxy of identifiable characters from modern urban India depicted with light-hearted mirth in a travel environment, the novel explores serious issues, such as the quest for an independent identity and economic independence, the violence within and outside our homes, the loneliness of old age and the need for constructive channelization of youthful energy. Spanning events across a little more than a year, Skeins depicts how self-expression and a supportive environment trigger a cataclysmic effect and stimulate the women to realize their dreams.
This book discusses the unique epidemiology of fungal infections in Asia, illustrating that the situation in these countries is different from that in Western countries in terms of the causative species, natural history and management strategies. Asia, the world’s largest continent and home to more than half the global population, has conditions that favor the growth of many fungi, including a number of unique species. Further, socio-economic conditions such as overcrowding, compromised health care facilities and lack of awareness add to the morbidity and mortality due to fungal diseases in this part of the world. Since the majority of Asian countries do not have good diagnostic mycology laboratories, antifungal management is often based on experience. The limited data from Asian countries suggest a very high incidence of fungal infections. This book addresses epidemiology of fungal infections in general and specific populations of Asia, fungal allergy, and diagnosis and management in resource-limited environments. The book is must read for busy clinicians, microbiologists and critical care providers.