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The Five Series Study
More than 200,000 U.S. military personnel participated in atmospheric nuclear weapons tests between 1945 and the 1963 Limited Nuclear Test Ban Treaty. Questions persist, such as whether that test participation is associated with the timing and causes of death among those individuals. This is the report of a mortality study of the approximately 70,000 soldiers, sailors, and airmen who participated in at least one of five selected U.S. nuclear weapons test series1 in the 1950s and nearly 65,000 comparable nonparticipants, the referents. The investigation described in this report, based on more than 5 million person-years of mortality follow-up, represents one of the largest cohort studies of military veterans ever conducted.
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Textbook of Cancer Epidemiology
This superb text gives a concise, systematic account of what is currently known about the epidemiology and primary prevention for most forms of human cancer. Part 1 provides an introduction to basic concepts in epidemiology, a description of the global burden of cancer, definitions and characterizations of the various measures used, and approaches used to reveal genetic determinants of cancer risk and integrate biologic markers in the epidemiogic research process. Part 2 contains chapters of uniform structure on over 20 types of cancer, providing clinical and pathological outlines, descriptive epidemiology, and a comprehensive account of risk factors and their etiological importance. Specific sections address somatic and germ cell mutations that play a role in the occurrence of particular forms of cancer.
Work-Related Musculoskeletal Disorders
Estimated costs associated with lost days and compensation claims related to musculoskeletal disorders-including back pains and repetitive motion injuries-range from $13 billion to $20 billion annually. This is a serious national problem that has spurred considerable debate about the causal links between such disorders and risk factors in the workplace. This book presents a preliminary assessment of what is known about the relationship between musculoskeletal disorders and what may cause them. It includes papers and a workshop summary of findings from orthopedic surgery, public health, occupational medicine, epidemiology, risk analysis, ergonomics, and human factors. Topics covered include the biological responses of tissues to stress, the biomechanics of work stressors, the epidemiology of physical work factors, and the contributions of individual, recreational, and social factors to such disorders. The book also considers the relative success of various workplace interventions for prevention and rehabilitation.
Theoretical and Mathematical Foundations of Human Health Risk Analysis
Scientists and regulators have struggled to define the role of theory, experiments, models and common sense in risk analysis. This situation has been made worse by the isolation of theory from modeling, of experimentation from theory, and of practical action from basic science. This book arises from efforts at regulatory agencies and industries to bring more science into health risk analysis so that society may better use limited resources to improve public health. This book covers: the characterization of exposure to pollutants and other sources of risk; the movement of pollutants into the body via inhalation; ingestion, dermal absorption, and exposures to radiation; the movement of a pollu...
Gene-Environment Interactions
Understanding the play between heredity and environment, and relating it to disease causation, is the task of ecogenetics. Gene-Environment Interactions: Fundamentals of Ecogenetics presents the first comprehensive survey of this discipline, reflecting its relationship with toxicology, epidemiology, pharmacology, public health, and other medical and biological fields. Divided into four sections, the text elucidates key basic and advanced topics: * Section 1 covers fundamentals, including the history of the discipline, a discussion of the molecular laboratory tools currently available to assess genotypes, using such measurements in molecular epidemiology studies, and the statistical issues in...
The Case-control Method
This title helps readers address a number of general and specific questions dealing with the case-control and other case-based methods, including questions of how to design and implement a case-control study that minimizes biases, how to analyze the data to appropriately deal with confounding variables and more.
