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The Second Edition of this single-authored volume integrates multiple disciplines of basic and clinical research to help clinicians further develop the best possible care for the rehabilitation of patients with neurologic diseases. From the readable descriptions of the structures and functions of pathways for movement and cognition, the reader comes to understand the potential for training induced, pharmacologic, and near-future biologic interventions to enhance recovery. Dr. Dobkin shows how functional neuroimaging serves as a marker for whether physical, cognitive, and neuromodulating therapies work and how they sculpt the plasticity of the brain. Themes, such as how the manipulation of se...
This book describes the applications of receptor techniques in many different areas in addition to conventional drug and neurotransmitter binding sites. It reviews humoral modulators such as a leukotrienes, interferon, platelet-derived growth factor, and novel endogenous ligands.
This comprehensive guide to MRI of the pregnant patient presenting with fetal or maternal diseases provides a practical, hands-on approach to the use of state-of-the-art MRI techniques and the optimization of sequences. It analyzes data obtained from maternal and fetal MRI examinations, reviews fast imaging techniques, details pitfalls related to fetal MRI and assesses methods for improving image resolution. Fetal pathological conditions and methods of prenatal MRI diagnosis are discussed according to organ system and the literature is reviewed. Interpretation of findings and potential artifacts are thoroughly considered with the aid of numerous high-quality illustrations. The book will be a detailed resource for radiologists, obstetricians, neonatologists and geneticists, as well as any other practitioner who wishes to gain an in-depth understanding of fetal and maternal MRI. In addition, it will serve as a reference source for technicians, researchers and students, as well as for any specialist who is planning to set up a fetal and maternal MRI service.
Since Benjamin Rush first introduced the disease of wills as the cause of alcoholism, a steady and slow infiltration of the disease model has infected how the church treats those who struggle with addictions. The first organization that truly sought to remove the soul care of addicts from the church was Alcoholics Anonymous (AA), through their bestselling The Big Book of AA and the introduction of the 12 Steps. AA's influence on how the church confronts addiction still reverberates today, with many of the ministries that address addiction firmly rooted in what can be found in AA literature. Addictions were once viewed as an issue caused by sin and best addressed through faith and prayer. Currently addiction is seen through the lens of disease. The ramifications are consequential as more church members are struggling with addictions than ever before. Tracing the progression of addiction from sin to disease will reveal that the SBC and its churches have been negligent in understanding the underlying foundations of AA and the influence that the medicalization of substance abuse has had on how churches approach what should be classified as a sin issue.
This book concerns how estrogens are synthesized in the brain and their two modes of action on behavior: a slow process involving gene transcription and a faster action at the cell membrane. The significance of the regulation and distribution of the estrogen synthesizing enzyme aromatase in the brain is also highlighted.
We live in an age of surveillance. In this book, the moral importance of this is explained through an examination of virtual identities.
Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.
Dr. Juan is that rarest of rarities, a scholar with a sense of humor. He fearlessly tours the brain's mysterious corridors, discussing such wide-ranging topics as phobias, compulsive water drinking, serial killers, the secrets of hypnotism, and the man who thought he was a cat. You will find this book absolutely engrossing. Do kleptomaniacs have a legitimate excuse to steal? Can excessive TV watching physically "shape" a child's growing brain? These answers and scores more fill Dr. Stephen Juan's fascinating and endlessly entertaining book The Odd Brain. Following up his popular first book, The Odd Body, Dr. Juan takes us on an animated tour of the enigmatic organ that sits on top of them al...
Epidemiological studies have associated tobacco consumption with a lower incidence of Alzheimer’s disease (AD) and Parkinson’s disease (PD). The neuroprotective effect of tobacco has been mainly attributed to the stimulation by nicotine of the a7 nicotinic acetylcholine receptors (nAChRs), which are implicated in neuronal survival, attention, and memory. A reduction in cholinergic function including lower levels of the expression of nAChRs in the hippocampus correlates with memory impairment in AD and schizophrenia. nicotine main metabolite cotinine shows similar neuroprotective and mnemonic properties. Also cotinine reduced Alzheimer’s pathology in a mouse model of the disease. Tobacco-derived compounds can be beneficial in a broad range of neurological disorders such as schizophrenia, AD, attention-deficit hyperactivity disorder, and PD as well as in diminishing tobacco withdrawal. In the latest years numerous new discoveries in this research area have been achieved and a Research Topic publication is needed.