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The Role of Inflammatory Mediators in the Failing Heart
Although clinicians have recognized the importance of inflammatory mediators in the pathogenesis of heart disease for well over 200 years, it has taken nearly as many years for clinicians and scientists to focus on the basic biological mechanisms by which inflammatory mediators contribute to the pathogenesis of cardiac disease states. Over the past decade there has been increasing interest in the potential role that inflammatory mediators, play in a variety of cardiac disease states, including chronic heart failure. The Role of Inflammatory Mediators in the Failing Heart provides a state-of-the-art review on inflammatory mediators and the failing heart. This book will serve both as a useful introduction to the field, as well as an update for those interested in the role of inflammatory mediators and the failing heart.
Heart Failure: A Companion to Braunwald's Heart Disease E-book
Dr. Douglas L. Mann, one of the foremost experts in the field, presents the 2nd Edition of Heart Failure: A Companion to Braunwald’s Heart Disease. This completely reworked edition covers the scientific and clinical guidance you need to effectively manage your patients and captures the dramatic advances made in the field over the last five years. Now in full color, this edition features eleven new chapters, including advanced cardiac imaging techniques, use of biomarkers, cell-based therapies and tissue engineering, device therapies, and much more. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, ...
Broken Hearts
A history illustrating the complexity of medical decision making and risk. Still the leading cause of death worldwide, heart disease challenges researchers, clinicians, and patients alike. Each day, thousands of patients and their doctors make decisions about coronary angioplasty and bypass surgery. In Broken Hearts David S. Jones sheds light on the nature and quality of those decisions. He describes the debates over what causes heart attacks and the efforts to understand such unforeseen complications of cardiac surgery as depression, mental fog, and stroke. Why do doctors and patients overestimate the effectiveness and underestimate the dangers of medical interventions, especially when doing so may lead to the overuse of medical therapies? To answer this question, Jones explores the history of cardiology and cardiac surgery in the United States and probes the ambiguities and inconsistencies in medical decision making. Based on extensive reviews of medical literature and archives, this historical perspective on medical decision making and risk highlights personal, professional, and community outcomes.
From Molecule to Men
From molecule to man: Medical research has indeed taken this direction, and major improvements of our understanding of the pathophysiology and epidemiology of disease have been achieved. The molecular basis of the congenital cardiovascular disorders has been extended from relatively few congenital malformations into everyday illnesses such as diabetes mellitus, hyperlipoproteinaemea, and arterial hypertension. The monogenic and, more difficult, polygenic basis for a vast majority of cardiovascular disorders are being defined more precisely from year to year. This book gives an overview of what has been achieved so far and defines the current position.
Cardiovascular Therapeutics
This companion to Braunwald's Heart Disease equips you with all of today's most effective therapeutic guidelines and management solutions for the full range of heart disease patients. It reflects the most recent standards for drug management as well as the latest in new technologies. Reorganized to mirror your changing practice, each cardiovascular-problem-based section offers a chapter on pharmacologic treatment (with a minimum of pathophysiology)...a chapter on catheter-based or minimally invasive interventions...and a discussion of surgical options. You'll also find a brand-new chapter on gene therapy and stem cell therapy, plus new chapters on many other rapidly developing areas of pract...
Heart Hypertrophy and Failure
Heart Hypertrophy and Failure brings together leading basic scientists and clinicians, presenting improved knowledge of the pathophysiology and treatment of the condition. The result is a synthesis of state-of-the-art information on molecular biology, cellular physiology and structure-function relationships in the cardiovascular system in health and disease. The papers presented describe fundamental mechanisms underlying changes in the cellular machinery during the development of cardiac hypertrophy and heart failure. Audience: Students, scientists, clinical and experimental cardiologists who seek to understand and manage the perplexing problems of hypertrophy and heart failure.
The Role of Nitric Oxide in Heart Failure
Research on nitric oxide (NO) is a very hot topic since 1998, when three prominent researchers were recognized by Nobel prize awards. Addresses clinically pertinent issues related to nitric oxide in the pathophysiology and therapeutics of heart failure. Chapters written by basic scientists and clinicians to emphasize translation character of research in nitric oxide. An excellent reference source for researchers, practitioners and students.
Vascular Endothelium in Human Physiology and Pathophysiology
Endothelial dysfunction is now regarded as an early marker of vascular disease and therefore an important target for therapeutic intervention and discovery of novel treatments. Ideal for both basic and clinical scientists, whether in industry or academia, and physicians, Vascular Endothelium in Human Physiology and Pathophysiology provides an up-to
Cardiology E-Book
With your heavy case load, you can't afford to waste time searching for answers. Cardiology, 3rd Edition, by Drs. Crawford, DiMarco, and Paulus, offers you just the practical, problem-based guidance you need to quickly overcome any clinical challenge. 8 color-coded sections cover the 8 major clinical syndromes of cardiovascular disease—each section a virtual "mini textbook" on its topic! 40 new chapters keep you up to date with the latest advances in the field, while more than 2,000 lavish, high-quality illustrations, color photographs, tables, and ECGs capture clinical manifestations as they present in practice. It’s current, actionable information that you can put to work immediately f...
Sudden Cardiac Death
This book draws on the established European guidelines from the ESCthat address the key issues in sudden cardiac death, such asidentifying individuals at risk prior to an episode of aventricular tachyarrhythmia or a sudden cardiac arrest, andresponding in a timely fashion to the person suffering the eventout-of-the-hospital. It presents an update on what is known aboutsudden cardiac arrest, from basic experimental studies to clinicaltrials, and serves as a complement to the ESC Core Syllabus on thissubject. Topics include epidemiology, genetics, arrhythmogenicmechanisms, risk stratification, autonomic nervous system andphenotypes. Disease states and special populations are alsocovered, as we...
