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Natural products continue to serve as sources for the development of new medicines. There is currently a revival of interest in the discovery of bioactive compounds with new chemical structures from natural sources, largely due to the fact that synthetic libraries have not yielded the expected number of developmental candidates in the pharmaceutical industry during the last decade. In addition, the emergence of clinically relevant pathogens that are becoming increasingly resistant to currently used medicines strengthens the notion that natural product research is urgently required. Considering the fact that almost 10% of bioactive compounds are of microbial origin, and that marine microorganisms are relatively poorly studied compared to their terrestrial relatives, marine microorganisms are regarded as the most potential-laden resource for drug discovery.
A trillion different microbial species have been evolving for some 3.5 billion years, producing ever more complex active secondary metabolites. The sea is a cauldron of a great diversity of useful and valuable compounds. This Special Issue focused on studies of marine microbe natural products for discovering compounds useful to humankind. Papers were collected that provide up-to-date information regarding the characterization of marine microbes’ metabolic diversity and the evaluation of the therapeutic potential of marine microbes’ metabolites. Most of the articles in this book deal with marine fungi, biological and chemical diversity, and their active metabolites. This may be a sign tha...
BLOOD STASIS: CHINA'S CLASSICAL CONCEPT IN MODERN MEDICINE covers the area of blood stasis in Traditional Chinese Medicine, drawing from a huge range of original Chinese material. The book discusses many Western diseases including diabetes, gynecological disorders, stroke, tumors, myocardial infarction, and the interaction of these with other pathological factors. The book also provides both classical and modern differentiations and treatments, including both herbs and acupuncture in all categories with appropriate case histories. - Thoroughly examines the concepts and processes of blood stasis in Traditional Chinese Medicine. - Draws on original translations from Chinese sources ranging from the classical era through modern times. - Describes, in full, the historical perspective of Chinese Medicine's presentation of blood stasis theory and also includes modern research for a balanced view of the effectiveness of blood stasis. - Highlights recent detailed analysis of blood stasis and herbs. - Incorporates real-life cases helped by blood stasis therapy.
Adopting a novel approach to the topic by combining theoretical knowledge and practical results, this book presents the most popular and useful computational and experimental methods applied for studying the stereochemistry of chemical reactions and compounds. The text is clearly divided into three sections on fundamentals, spectroscopic and computational techniques, and applications in organic synthesis. The first part provides a brief introduction to the field of chirality and stereochemistry, while the second part covers the different methodologies, such as optical rotation, electronic circular dichroism, vibrational circular dicroism, and Raman spectroscopy. The third section then goes on to describe selective examples in organic synthesis, classified by reaction type, i.e. enantioselective, chemoselective and stereoselective reactions. A final chapter on total synthesis of natural products rounds off the book. A valuable reference for researchers in academia and industry working in the field of organic synthesis, computational chemistry, spectroscopy or medicinal chemistry.
Selected, peer reviewed papers from the 2010 International Conference on Advanced Measurement and Test (AMT 2010), May 15-16, 2010, Sanya, P.R. China.
This book focuses on reservoir surveillance and management, reservoir evaluation and dynamic description, reservoir production stimulation and EOR, ultra-tight reservoir, unconventional oil and gas resources technology, oil and gas well production testing, and geomechanics. This book is a compilation of selected papers from the 11th International Field Exploration and Development Conference (IFEDC 2021). The conference not only provides a platform to exchanges experience, but also promotes the development of scientific research in oil & gas exploration and production. The main audience for the work includes reservoir engineer, geological engineer, enterprise managers, senior engineers as well as professional students.
At the crossing of centuries, it is very important to review the main problems and research in theoretical physics. This was the purpose of the International Workshop on Frontiers of Theoretical Physics, allowing the interchange of ideas among people with different expertise.The proceedings can be divided into two parts: (1) general view talks about string, particle physics, nuclear physics, etc. given by Profs. T Yoneya, M Kobayazhi, A Sanda, Z Li and F Sakata; (2) research related to many important fields, such as quantum field theory, string theory, particle physics, condensed matter physics, nuclear physics and mathematical physics.
Shaolin Kungfu has been considered by many as the best martial art in the world. But kungfu is just one of the three treasures of Shaolin, the other two being chi kung and Zen. For the first time ever, this inspiring book, written by an internationally acclaimed Shaolin Grandmaster, brings to you the crystallization of Shaolin wisdom and practice spanning many centuries. Its scope and depth is amazing, touching on, among many other things, poetry and enlightenment. Yet it is written in a language easy to understand. Profound concepts and difficult techniques are explained systematically with many illustrations. The book includes: * The background and scope of kungfu. * Form and combat applications. * Principles and methods of force training. * Energy training and mind training. * Secrets of the masters. * Traditional Chinese weapons. * Maintaining one’s health and vitality and the healing of so-called incurable diseases. * Interesting stories and legends of Shaolin. * Zen and spiritual development.