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Diffuse Low-Grade Gliomas in Adults
The second edition of this well-received volume has been revised and updated to reflect the advances in pathological classification and molecular epidemiology of diffuse low-grade gliomas (DLGG) in adults and offers an updated review on individualized therapies. This book presents the latest research pertaining to the diagnosis, genetics, therapy and management of DLGGs. It extensively covers recent research on the natural history of DLGGs and their interaction with the brain and reviews the new diagnostic and therapeutic strategies which increase survival and quality of life of the patient. New topics covered are the management of DLGGs during pregnancy, functional rehabilitation of patients with DLGG and the onco-functional balance in DLGG, among others. The reader will have the opportunity to gain insight in both clinical and basic science aspects of this type of tumor and learn about the application of novel imaging techniques such as diffussion tensor imaging. Edited by a leading expert in the field and authored by a team of recognised specialists, this book is a valuable resource for medical oncologists, neuro-oncologists and neurologists.
Low-Grade Glioma, An Issue of Neurosurgery Clinics of North America
This issue of Neurosurgery Clinics, guest edited by Drs. Guy McKhann and Hugues Duffau, with consulting editors Russell R. Lonser and Daniel K. Resnick, will focus on Low-Grade Glioma. Topics includes, but are not limited to, Epidemiology and Molecular Epidemiology; WHO Pathological and Molecular Classification; Molecular Pathogenesis; Glioma Cell Migration and Heterogeneity; Clinical Presentation, Natural History, and Prognosis; LGG Epilepsy; MRI, fMRI, DTI, Molecular Imaging; Brain Mapping Techniques in LGG; Surgical Adjuncts to Increase EOR iMRI, Flourescence, Raman Histology; Mapping Cognition and Emotion; Extent of Resection; EOR vs Molecular Classification; Chemotherapy Treatment and Trials; Radiotherapy Treatment and Trials; Higher Order Surgical Questions; and Building a Glioma Practice.
Brain Mapping
The goal of this book is to make a link between fundamental research in the field of cognitive neurosciences, which now benefits from a better knowledge of the neural foundations of cerebral processing, and its clinical application, especially in neurosurgery – itself able to provide new insights into brain organization. The anatomical bases are presented, advances and limitations of the different methods of functional cerebral mapping are discussed, updated models of sensorimotor, visuospatial, language, memory, emotional, and executive functions are explained in detail. In the light of these data, new strategies of surgical management of cerebral lesions are proposed, with an optimization of the benefit–risk ratio of surgery. Finally, perspectives about brain connectivity and plasticity are discussed on the basis of translational studies involving serial functional neuroimaging, intraoperative cortico-subcortical electrical mapping, and biomathematical modeling of interactions between parallel distributed neural networks.
Diffuse Low-Grade Gliomas in Adults
This book presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualised therapy for this kind of tumour. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book.
New Therapeutic Strategies in Low-Grade Gliomas
Low-grade glioma (LGG) is a brain infiltrative neoplasia, often invading cortical and subcortical functional structures. It affects young active patients, who usually present with seizures. This work gives insights into different therapeutic strategies that need to be considered for each patient, and the parameters that can help decision making.
New Insights Into Functional Mapping in Cerebral Tumor Surgery
The rationale of brain tumour surgery depends on two antagonist goals: on one hand, to optimise the quality of resection, on the other hand, to minimise the risk of permanent postoperative deficit. However, due to the physiological interindividual anatomo-functional variability, increased in cases of cerebral tumours because of the plastic potential of the brain, a study of the interactions between the lesion and the host seems mandatory - in order to understand the individual dynamic organisation of the brain, then with the goal to avoid postsurgical sequelae.In this way, new methods of functional brain mapping can be useful for the neurosurgeon. First, before surgery, non-invasive function...
L'erreur de Broca
Imaginez qu'on puisse vous opérer d'une tumeur au cerveau sans vous endormir, et qu'en affinant le geste médical on sauve non seulement votre vie mais toutes les capacités de cet organe... Imaginez qu'on puisse aller jusqu'à amputer votre cerveau de la zone du langage, la fameuse " aire de Broca ", sans vous priver pour autant de la parole... Science-fiction ? En aucun cas. C'est ce qu'a prouvé le professeur Duffau qui, à ce jour, a opéré plus de six cents tumeurs cérébrales, sans séquelles. Décrié à ses débuts, il est aujourd'hui mondialement reconnu et consulté pour sa technique spectaculaire. Après une lutte acharnée pour rompre avec les dogmes encore en vigueur, il a révolutionné la neurologie et mis fin à une croyance erronée vieille de cent cinquante ans. En effet, le cerveau n'est pas divisé en zones indépendantes comme on le croyait, mais organisé en réseaux interactifs et doté d'une étonnante plasticité. Il est donc capable de s'adapter ou de se remodeler en permanence, offrant aux patients une récupération et une qualité de vie qu'on imaginait jusqu'ici impossibles. Un immense message d'espoir
Medical Imaging and Augmented Reality
Here are the refereed proceedings of the Third International Workshop on Medical Imaging and Augmented Reality, MIAR 2006, held in Shanghai, China, August 2006. The book presents 45 revised full papers together with 4 invited papers. The papers are organized in topical sections on shape modeling and morphometry, patient specific modeling and quantification, surgical simulation and skills assessment, surgical guidance and navigation, image registration, PET image reconstruction, and image segmentation.
Advances and Technical Standards in Neurosurgery, Vol. 35
S. Price: Advances in imaging low grade gliomas - M.J. Riemenschneider, G. Riefenberger: Molecular neuropathology of low grade gliomas and its clinical impact - I . Whittle: What is the place of conservative management for adult supratentorial low grade glioma - D. Kurzwelly, U. Herrlinger, M. Simon: Seizures in patients with low grade gliomas -- incidence, pathogenesis, surgical management, and pharmacotherapy - L. Bello et al: Present day's standards in microsurgery of low grade gliomas - B. Baumert: Is there a place for radiotherapy in low grade gliomas - F.W. Kreth, N. Thon, J.-C. Tonn
Clinical Functional MRI
This is the first textbook on clinical fMRI. It is devoted to preoperative fMRI in patients with brain tumors and epilepsies, which are the most well-established clinical applications. State-of-the-art fMRI procedures are presented, with detailed consideration of the physiological and methodological background, imaging and data processing, normal and pathological findings, diagnostic possibilities and limitations, and other related techniques.
