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Advances in Human Factors in Architecture, Sustainable Urban Planning and Infrastructure
This book discusses human factors research directed towards realizing and assessing sustainability in the built environment and architecture. It reports on advanced engineering methods for sustainable infrastructure design, architecture as well as on assessments of the efficient methods and the social, environmental, and economic impact of various designs and projects. The book covers a range of topics, including the use of recycled materials in architecture, ergonomics in buildings and public design, sustainable design for smart cities, design for the aging population, industrial design, human scale in architecture, and many more. Based on the AHFE 2019 International Conference on Human Factors in Architecture, Sustainable Urban Planning and Infrastructure, held on July 24-28, 2019, in Washington D.C., USA, it offers various perspectives on sustainability and ergonomics. As such, it is a valuable reference resource for designers, urban engineers, architects, infrastructure professionals, public infrastructure owners, policy makers, government engineers and planners, as well as operations managers and academics active in urban and infrastructure research.
Mechanisms of Neurodegeneration in Amyotrophic Lateral Sclerosis and Related Disorders
Motor neuron diseases (MNDs) comprise a large and heterogeneous group of disorders in which the impairment of neuromuscular unity is the major pathological hallmark, causing severe morbidity to individuals, and frequently leading to death due to respiratory failure. The incidence of MNDs varies in different populations; however, the most prevalent, Amyotrophic Lateral Sclerosis, is estimated to occur globally in around 1/2 per 100 000. As of today, a myriad of pathogenic variants located at more than a hundred genes and loci have been associated with this complex group of entities. Functional studies aiming to understand their physiological impact, both using stem cell and animal models, hav...
Celebrating the Diversity of Genetic Research to Dissect the Pathogenesis of Parkinson's Disease
We would like to acknowledge Prof Rejko Krueger, from University of Luxembourg, who acted as a coordinator contributing to the preparation of the proposal for this Research Topic as part of the GEoPD.
