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Volume 5 of Biomembranes covers an important group of membrane proteins, the ATPases. The P-type ATPases couple the hydrolysis of ATP to the movement of ions across a membrane and are characterized by the formation of a phosphoyrlated intermediate. Included are the plasma membrane and muscle sarcoplasmic reticulum Ca2+ -ATPases, the (Na+ -K+) -ATPase, the gastric (H+ -K+) -ATPase, the plasma membrane H+ -ATPase of fungi and plants, the Mg2+ - transport ATPase, the Salmonella typhimurium, and the K+ -ATPase of Escherichia coli, KdpB. The other important classes of ATPase in eukaryotic systems are the vacuolar H+ -ATPases and the F0F1 ATP synthase, and, in bacteria, the anion-translocating ATPases, responsible for resistance to arsenicals and antimonials, and the (Na+ -Mg2+) -ATPase of Acholeplasma. Finally, eukaryotic systems contain a variety of ectonucleotidases important, for example, in hydrolysis of extracellular ATP released as a cotransmitter from cholinergic and adrenergic nerve terminals. Volume 5 of Biomembranes explores structure-function relationships for these mebrane-bound ATPases.
Advances in Inorganic Chemistry and Radiochemistry
A classic nephrology reference for over 25years, Seldin and Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the new...
Long considered the bible of thoracic surgery, this comprehensive two-volume textbook guides you through virtually every open and endoscopic surgical technique with expert commentary by the leaders in thoracic surgery from around the world. Coverage includes extensive sections on lung cancer and other pulmonary tumors. All facets of thoracic disease are covered from anatomy and embryology to diagnostics, including extensive radiological sections. Multidisciplinary contributions on medical treatment, radiation oncology, and surgery and anesthesia are included. Highlights include new material on minimally invasive procedures and thoroughly updated diagnostic and treatment information. Operative checklists are included in procedural chapters, and procedures are presented as bulleted to-do lists wherever possible. A companion Website will offer the fully searchable text with all images and video clips of selected procedures.
Although the role of liposomes in drug targeting has been discussed extensively in several reviews and books, there has been no comprehensive coverage of related methodology. This book constitutes the first attempt to put together all aspects of lipsome technology as applied to medical sciences. Volume II describes procedures for the entrapment of a number of drugs, including genetic material, into selected types of lipsomes.
This book brings together the essential evidence and policy opportunities regarding the global importance of soil carbon for sustaining Earth's life support system for humanity. Covering the science and policy background for this important natural resource, it describes land management options that improve soil carbon status and therefore increase the benefits that humans derive from the environment. Written by renowned global experts, it is the principal output from a SCOPE rapid assessment process project.