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The Veteran
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Journal
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The Menisci
This book is a comprehensive journey through the pathogenesis and treatment of meniscal pathology. It details the elements that are necessary to properly understand, diagnose, and treat meniscal tears, ranging from vertical tears to radial tears and root avulsions. Treatment techniques are thoroughly described and illustrated, with presentation of the latest evidence on outcomes. The algorithmic treatment of meniscal tears has undergone a rapid transformation. We have progressed from the initial treatments involving removal of the meniscus using an open technique, to the performance of partial meniscectomies and complex meniscal repairs by means of an arthroscopic technique. The current trea...
BACE
BACE inhibitors and their use in the treatment of Alzheimer's Disease BACE (β-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery. This book details the story of the discovery of BACE and its role in AD and comprehensively discusses: The development of BACE inhibitors as therapeutics fo...
Research on Adaptive Wall Wind Tunnels
The objective of this research was to investigate the utility of the Calspan self-correcting wind tunnel for minimizing or eliminating wall interference effects in two-dimensional transonic flows when shock waves from the test model extend to the tunnel walls. This report summarizes the experimental research performed with two-dimensional airfoils in the Calspan self-correcting wind tunnel and the theoretical research accomplished in support of the experiments. The experiments were performed with airfoil models having 4% and 6% solid blockage. The initial experiments with the 6%-blockage model were devoted to determining a practical mode of operation when shock waves from the model extend to...
Congressional Record
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