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In Targets for Cancer Chemotherapy: Transcription Factors and Other Nuclear Proteins, a panel of leading basic researchers, pharmaceutical scientists, and clinical oncologists explain in detail the therapeutically-relevant protein targets that contribute to cancer pathology and spell out their implications for cancer drug discovery and clinical application. The authors identify and illuminate selected transcription factor oncoproteins and tumor suppressors, together with nuclear proteins that are central to the phenotype of the tumor cell involved in chromatin control. The emphasis is on new targets and approaches to cancer treatment derived from the cancer cell cycle, gene control targets, and angiogenesis.
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Quality of Life: From Nursing and Patient Perspectives, Third Edition is a comprehensive text that offers a unique perspective on quality of life by reflecting the voices of patients and families receiving or having received care for cancer. It is an ideal reference for oncology nursing students and oncology nurses in a variety of settings, including inpatient units, outpatient clinics, ambulatory care centers, cancer centers, research centers, home care agencies, and hospices. Topics explore evolution of quality of life in oncology, theories and conceptual models, life methodological and measurement issues, clinical implications, cancer survivorship, and quality of life stories by patients and families. Completely updated and revised, this new edition contains two new research chapters and new material on chronic illness, measuring quality of life in different age groups, and patient perspectives.
There are times in in life, when it takes great courage to learn to stand up for yourself,and find your true authentic identity and purpose. This book is about the journey of self-discovery, learning to let go of past hurts; and ultimately discovering the truly "Awesome" person you were intended to be. For anyone who has ever struggled with the issues of self-identity and self-worth; and found the courage to face their fears and follow their dreams.
The contributors to this volume have provided a detailed and integrated introduction to the behavioural, anatomical, and physiological changes that occur in the auditory system of developing animals. Edwin W Rubel is Virginia Merrill Bloedel Professor of Hearing Sciences at the Virginia Merrill Bloedel Hearing Research Center at the University of Washington, Arthur N. Popper is Professor and Chair of the Department of Zoology at the University of Maryland, while Richard R. Fay is Associate Director of the Parmly Hearing Institute and Professor of Psychology at Loyola University of Chicago. Each volume in this series is independent and authoritative; taken as a set, the series will be the definitive resource in the field.
Issues for 1860, 1866-67, 1869, 1872 include directories of Covington and Newport, Kentucky.
This book provides an introduction to Acoustic Emission Testing and its applications to different materials like concrete, steel, ceramics, geotechnical materials, polymers, biological structures and wood. Acoustic Emission Techniques (AET) techniques have been studied in engineering for a long time. The techniques are applied more and more to practical investigations and are more and more standardized in codes. This is because the degradation of structures due to ageing urgently demand for maintenance and rehabilitation of structures in service. It results in the need for the development of advanced and efficient inspection techniques. In mechanical engineering and concerning the monitoring...