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This edited volume discusses the impact of several major databases containing historical longitudinal population data. The creation and development of these databases have greatly expanded research possibilities in history, demography, sociology, and other disciplines. The present collection includes seven contributions, on eight databases, that had a wide impact on research in various disciplines. Each database had its own unique genesis and readers are informed about how these databases have changed the course of research in historical demography and related disciplines, how settled findings were challenged or confirmed, and how innovative investigations were launched and implemented. The volume serves as an essential resource for scholars in the field of historical life course studies, offering insights into the transformative power of these databases and their potential for future advancements.
In the early 1990s, a new concept was coined: ‘evidence-based medicine’ (EBM). After a remarkably short time, EBM was virtually all-pervasive in medicine and healthcare throughout the world. Even outside the domain of healthcare, the new concept became fashionable, for example in the shape of (pleas for) ‘evidence-based management’ and ‘evidence-based policy’. In short, ‘evidence-based’ developed into one of the mantras of the current era. This book uses history as a tool to gain insight into the highly influential, but also elusive and multifaceted phenomenon of EBM. As such, A Doctor’s Order is a ‘must read’ for patients, professionals, managers and policy makers in healthcare as well as for anyone who is interested in understanding the present socio-political order.
In his thesis, Matthias Junk takes an innovative approach to assess the local structure and dynamics of biological and synthetic amphiphilic macromolecules capable of transporting small molecules. Replacing the latter with stable radicals, he uses state-of-the-art electron paramagnetic resonance (EPR) spectroscopy to describe the highly relevant transport function from the viewpoint of the guest molecules. Such, he demonstrates that the functional structure of human serum albumin in solution significantly differs from its crystal structure – a consequence of the protein’s adaptability to host various endogenous compounds and drug molecules. Further, he shows that the thermal collapse of thermoresponsive hydrogels and dendronized polymers leads to static and dynamic heterogeneities on the nanoscale. These heterogeneities bear consequences for the material’s hosting properties and enable unforeseen complex catalytic functionalities.
Sets forth an important group of environmentally friendly organic reactions With contributions from leading international experts in organic synthesis, this book presents all the most important methodologies for stereoselective organocatalysis, fully examining both the activation mode as well as the type of bond formed. Clear explanations guide researchers through all the most important methods used to form key chemical bonds, including carbon-carbon (C–C), carbon-nitrogen (C–N), and carbon-halogen (C–X) bonds. Moreover, readers will discover how the use of non-metallic catalysts facilitates a broad range of important reactions that are environmentally friendly and fully meet the stand...
Autonomic dysfunction is a major and poorly understood consequence of spinal cord injury. It is a cause of very serious disability and requires much more research. It should be a focus of treatment strategies. This book will be of interest to anyone involved in research and treatment of spinal cord injury since it helps to explain the tremendously negative impact on the body caused by cord injury that is not as obvious as paralysis and loss of sensation. It contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions.The book begins with...
With contributions from world-renowned figures such as Niall Ferguson and Adair Turner, this volume investigates how financial institutions and markets have undergone or reacted to past pressures, and the regulatory responses that emerged as a result.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Organometallic chemistry is an interdisciplinary science which continues to grow at a rapid pace. Although there is continued interest in synthetic and structural studies the last decade has seen a growing interest in the potential of organometallic chemistry to provide answers to problems in catalysis, synthetic organic chemistry and also in the development of new materials. This Specialist Periodical Report aims to reflect these current interests, reviewing progress in theoretical organometallic chemistry, main group chemistry, the lanthanides and all aspects of transition metal chemistry. Volume 31 covers literature published during 2001. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.
Highlighting the progress made by researchers in using Web-based surveys for data collection, this timely volume summarizes the experiences of leading behavioral and social scientists from Europe and the US who collected data using the Internet. Some chapters present theory, methodology, design, and implementation, while others focus on best practice examples and/or issues such as data quality and understanding paradata. A number of contributors applied innovative Web-based research methods to the LISS panel of CentERdata collected from over 5,000 Dutch households. Their findings are presented in the book. Some of the data is available on the book website. The book addresses practical issues...
Focusing on an important class of compounds in organic synthesis, this text features contributions by leading experts, and delivers the quality expected from the “Patai Series.”