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Prior to 1862, when the Department of Agriculture was established, the report on agriculture was prepared and published by the Commissioner of Patents, and forms volume or part of volume, of his annual reports, the first being that of 1840. Cf. Checklist of public documents ... Washington, 1895, p. 148.
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Psychedelic compounds use has a rich and complicated history spanning through ancient cultures, modern medical use, cultural movements and national and international politics. With the latest resurgence of use of these compounds in mental health and medical conditions, we are just scratching the surface of understanding the mechanisms that underlie these drugs' effects and their ways of action in the single body and in society as a whole.
Dieses Fachbuch legt den Schwerpunkt auf konkrete Methoden und die jüngsten Fortschritte bei der Anwendung von Nanotechnologie für die Entwicklung neuer medikamentöser Therapieansätze und die medizinische Diagnostik. Von den Grundlagen der Nanopharmazie, einschließlich Charakterisierung und Herstellungsverfahren, bis hin zur Rolle von Nanopartikeln und Wirkstoffen wird das Fachgebiet umfassend dargestellt. Anwendungsbeispiele beziehen sich auf Fragestellungen bei der Medikamentenentwicklung und die Übertragung auf die klinische Praxis, Marktchancen und Aspekte der industriellen Vermarktung. Die beschriebenen Anwendungen stammen aus der Behandlung von Krebserkrankungen und weiteren wichtigen Therapiebereichen wie Infektionskrankheiten und Dermatologie. Abgerundet wird das Fachbuch durch eine ausführliche Erörterung sicherheitsrelevanter, rechtlicher und gesellschaftlicher Fragen. Geschrieben von einem erstklassigen Team von Herausgebern und Autoren, die zu den führenden Experten in Europa und den USA sowie zu den Pionieren der Nanopharmazie gehören.
The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at minimum a working knowledge of each of the abovementioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop
This handbook--a sequel to the widely used Handbook of Optical Constants of Solids--contains critical reviews and tabulated values of indexes of refraction (n) and extinction coefficients (k) for almost 50 materials that were not covered in the original handbook. For each material, the best known n and k values have been carefully tabulated, from the x-ray to millimeter-wave region of the spectrum by expert optical scientists. In addition, the handbook features thirteen introductory chapters that discuss the determination of n and k by various techniques.* Contributors have decided the best values for n and k* References in each critique allow the reader to go back to the original data to examine and understand where the values have come from* Allows the reader to determine if any data in a spectral region needs to be filled in* Gives a wide and detailed view of experimental techniques for measuring the optical constants n and k* Incorporates and describes crystal structure, space-group symmetry, unit-cell dimensions, number of optic and acoustic modes, frequencies of optic modes, the irreducible representation, band gap, plasma frequency, and static dielectric constant
This book provides a comprehensive and up-to-date overview of all the upper and lower airways disorders and broadens their understanding by combining ENT and pulmonology disciplines. The volume opens with a general overview on the airways, before describing symptoms, infections and allergies. In addition to the upper airway tumors, specific lower, and upper airway disorders, other topics addressed by the book are pediatric lower airway disorders, sleep related breathing disorders, trauma, reflux, and interventional pulmonology. The closing part discusses the airway protection and includes a chapter on gender and pulmonary diseases. Written by experts in the fields, the book is a valuable resource for both specialists and trainees in ENT, pulmonology, and pediatrics.
Infrastructure Possibilities and Human-Centered Approaches With Industry 5.0 is a research book that serves as a comprehensive exploration of the potential impact of Industry 5.0 and the research opportunities presented by it, a new era of industrial revolution that integrates advanced technologies with human expertise and creativity. This book delves into the transformative effects of Industry 5.0 on society, with a particular focus on human-centric approaches and the key areas of agriculture, transportation, healthcare, and more. The book examines the revolutionary impact of Industry 5.0 in various domains. It explores the application of AI and machine learning in revolutionizing agricultu...