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Neuroplasticity refers to the ability of the Central Nervous System (CNS) to alter its structure and function in response to a variety of physiological and pathological processes such as development, cognition, injury or neurological diseases. Since more than four decades, studies on synaptic plasticity in the context of memory and learning attracted a remarkable interest. Soon after first seminal works on synaptic plasticity were published, research in this field was extended by studies on non-synaptic as wells as structural plasticity towards a goal to understand cellular and molecular determinants of cognition. Over the past two decades, yet two additional crucial players in neuroplastic ...
The book is intended for all those who are interested in application problems related to dynamical systems. It provides an overview of recent findings on dynamical systems in the broadest sense. Divided into 46 contributed chapters, it addresses a diverse range of problems. The issues discussed include: Finite Element Analysis of optomechatronic choppers with rotational shafts; computational based constrained dynamics generation for a model of a crane with compliant support; model of a kinetic energy recuperation system for city buses; energy accumulation in mechanical resonance; hysteretic properties of shell dampers; modeling a water hammer with quasi-steady and unsteady friction in viscoelastic conduits; application of time-frequency methods for the assessment of gas metal arc welding conditions; non-linear modeling of the human body’s dynamic load; experimental evaluation of mathematical and artificial neural network modeling for energy storage systems; interaction of bridge cables and wake in vortex-induced vibrations; and the Sommerfeld effect in a single DOF spring-mass-damper system with non-ideal excitation.
This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for doctors in neurology and psychiatry alike.
This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing. The powerful potential of hNSC to generate and repair the developing and adult CNS has been confirmed by numerous experimental in vitro and in vivo studies. The book presents methods for hNSC derivation and discusses the mechanisms underlying NSC in vitro fate decisions and their in vivo therapeutic mode of action. The long-standing dogma that the human central nervous system (CNS) lacks the ability to regenerate was refuted at the end of the 20th century, when evidence of the pr...
The use of machines has changed the workplaces of today. While machinery is still not able to perform certain jobs that require creative or non-routine functions, their continuous advancements have shifted the dynamic between organizations and manual laborers. Strategic Imperatives and Core Competencies in the Era of Robotics and Artificial Intelligence focuses on contemporary organizations and their use of new competencies. Featuring coverage on new skill identification and best practices for management, this book is essential for professionals, administrators, researchers, and students seeking current research on the latest developments in technological applications in the workplace.
This volume is part of collection of contributions devoted to analytical and experimental techniques of dynamical systems, presented at the 15th International Conference “Dynamical Systems: Theory and Applications”, held in Łódź, Poland on December 2-5, 2019. The wide selection of material has been divided into three volumes, each focusing on a different field of applications of dynamical systems. The broadly outlined focus of both the conference and these books includes bifurcations and chaos in dynamical systems, asymptotic methods in nonlinear dynamics, dynamics in life sciences and bioengineering, original numerical methods of vibration analysis, control in dynamical systems, optimization problems in applied sciences, stability of dynamical systems, experimental and industrial studies, vibrations of lumped and continuous systems, non-smooth systems, engineering systems and differential equations, mathematical approaches to dynamical systems, and mechatronics.
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