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Clinical Neurimmunology is the major reference text in the field, providing broad and comprehensive coverage of the interaction between the nervous and immune systems in both normal and diseased states. Understanding this interaction is fundamental to developing therapeutic approaches to disease and injury of the nervous system that are currently only marginally amenable to therapy. Neuroimmunology is a well-recognised and growing specialty world wide, both at the basic science and clinical level. It is a fast moving field and this is the most up to date text available. Chapters are dedicated to the role of the immune system in disorders affecting both the central and peripheral nervous syst...
This volume is designed to be kept close at hand as a ready reference and a guide to laboratory procedures. It is based on tissue culture manuals used for a number of years at international courses on tissue culture at the University of Saskatchewan, made possible by the generous support of the Canadian Council of Animal Care and the Medical Research Council of Canada. Sergey Fedoroff Arleen Richardson The second edition of Protocols for Neural Cell Culture adheres to the prin ciples enunciated in the first edition, but the content has been extensively revised and expanded. Two new chapters have been added to reflect the increased interest in the development and differentiation of the nervou...
Multiple Sclerosis: The History of a Disease won a 2005 ForeWord Book of the Year Silver Medal! The basic facts about multiple sclerosis are well known: it is the most common neurologic disease of young adults, usually beginning with episodic attacks of neurologic symptoms, then entering a progressive phase some years later. Its onset has an average age of 30, and occurs in about 1 in 500 individuals of European ancestry living primarily in temperate climates. There appears to be a complex interaction between a genetic predisposition and an environmental trigger that initiates the disease. But these facts do not convey the impact of the disease on the people whose lives it affects. In this e...
A new scientific discipline, acknowledged 65 years after its discovery, was the focus of the first Conference on Neuroimmune Biology in Canada. The papers presented at the conference, and in this volume, are dedicated to Dr. Hans Selye who is recognized as discovering the existence of a hypothalamic-pituitary-adrenal-thymus axis. This axis plays an important role in the adaptation of higher animals and man to various physical, chemical, biological and emotional challenges.The conference and participants also honored Dr. Andor Szentivanyi whose opening paper, "Studies on the hypothalamic regulation of histamine synthesis", is contained in the introduction to this book. Dr. Szentivanyi has ded...
This handbook is a collection of clinical narratives that underscore the heterogeneous and unpredictable presentation of multiple sclerosis (MS) and give real-world clinical context to recent drug developments. This accessible and concise publication is intended to be used by a wide range of medical professionals, from specialist neurologists to medical trainees with an interest in neurology. An ideal clinical resource, Case Studies in Multiple Sclerosis provides an evidence-based discussion of each case, with an aim to enhance effective diagnosis and treatment of patients with MS and MS-related conditions.
A Primer of Neuroimmunological Disease is a significant new resource for anyone interested in conditions such as multiple sclerosis(MS), myasthenia gravis, and neurological infections. It is a practical and balanced guide to the diagnosis and treatment of neuroimmunological disease. A Primer of Neuroimmunological Disease distinguishes itself by providing a range of features not generally included in texts on neuroimmunology. These include broad presentation of information in the form of figures and tables; strong cohesion among topics by focusing on a few prototypic neuroimmunological diseases, which serve as a foundation from which to explore other neuroimmunological diseases; a single author perspective, with references across chapters; and a focus on the overlap between neuroimmunological and neuroinfectious diseases. Neurologists, immunologists, infectious disease specialists, neuroscientists and others interested in neuroimmunological diseases such as MS will find A Primer of Neuroimmunological to be a state-of-the-art resource.
Multiple Sclerosis: Current Status and Strategies for the Future identifies promising areas of multiple sclerosis (MS) research based on a strategic analysis of the current state of knowledge. The report was written by the Institute of Medicine (IOM) Committee on MS Research Strategies, and on April 2001, the Committee held a workshop to advance research recommended by the report. The specific goals of the workshop were to disseminate information about the report, foster collaboration, and serve as a launch pad for implementation of the report's recommendations. Summary of a Workshop on Research in Multiple Sclerosis, April5-6,2001 presents the reports from each breakout group and summarizes the plenary session discussion. This workshop summary contains particular viewpoints attributed to individual participants or to groups of participants (including breakout groups), but does not contain statements about what "the workshop" or "all its participants" concluded.
Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people glob...
Discusses the controversial viewpoints regarding stem cell research.