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Current Trends in Monoclonal Antibody Development and Manufacturing
Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups involved in the development of this important class of molecules, monoclonal antibodies products will become increasingly prevalent over the next decade. Recently the regulatory review of monoclonal antibodies has been moved from Center for Biologics and Research to the Center for Drug Evaluation a...
Pharmaceutical Inhalation Aerosol Technology, Third Edition
This fully revised and updated third edition of Pharmaceutical Inhalation Aerosol Technology encompasses the scientific and technical foundation for the rationale, design, componentry, assembly and quality performance metrics of therapeutic inhalers in their delivery of pharmaceutical aerosols to treat symptoms or the underlying causes of disease. It focuses on the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery. The expanded scope considers previously unaddressed aspects of pharmaceutical inhalation aerosol technology and the patient interface by including aerosol delivery, lung deposition and cleara...
Analytical Ultracentrifugation
Analytical Ultracentrifugation, the latest volume in Methods in Enzymology, focuses on analytical ultracentrifugation. The scope of this technique has greatly expanded in recent years due to advances in instrumentation, algorithms and software. This volume describes the latest innovations in the field and in the applications of analytical ultracentrifugation in the analysis of macromolecules, macromolecular assemblies, and biopharmaceuticals. - Timely contribution that describes a rapidly changing field - Leading researchers in the field - Broad coverage: instrumentation, basic theory, data analysis, and applications
Uncle John's Bathroom Reader Presents Flush Fiction
Quick fiction for readers on the go! Quick fiction for readers on the go! Uncle John’s Bathroom Reader Presents Flush Fiction is a tantalizing collection of 88 short-short stories custom-picked for the Bathroom Reader aficionado. We scoured the nation for talented writers and asked them to send us their best quick reads. The result: mysteries, horror, sci-fi, adventure, plenty of laughs--and a few gasps--in these startling short stories. They’re like little movies for your mind! Some titles to entice you: * “Nothing” * “Mr. Agreeable” * “Dead Man’s Float” * “The Unseeing Eye” * “Checking out a Geezer” * “My First Foreign Woman and the Sea” * “Rusty the Pirate (A Historical Feghoot)” * “The Loom of Doom Galls Mainly in the Tomb” What are these stories about? Check out Flush Fiction and you won’t be disappointed!
Implementing IBM CICS JSON Web Services for Mobile Applications
This IBM® Redbooks® publication provides information about how you can connect mobile devices to IBM Customer Information Control System (CICS®) Transaction Server (CICS TS), using existing enterprise services already hosted on CICS, or to develop new services supporting new lines of business. This book describes the steps to develop, configure, and deploy a mobile application that connects either directly to CICS TS, or to CICS via IBM Worklight® Server. It also describes the advantages that your organization can realize by using Worklight Server with CICS. In addition, this Redbooks publication provides a broad understanding of the new CICS architecture that enables you to make new and...
Handbook of Pharmaceutical Granulation Technology
Theoretical discussions covering granulation and engineering perspectives. Covers new advances in expert systems, process modelling and bioavailability Chapters on emerging technologies in particle engineering Updated Current research and developments in granulation technologies
