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Forensic DNA Typing: Principles, Applications and Advancements
The book explores the fundamental principles, advances in forensic techniques, and its application on forensic DNA analysis. The book is divided into three modules; the first module provides the historical prospect of forensic DNA typing and introduces fundamentals of forensic DNA typing, methodology, and technical advancements, application of STRs, and DNA databases for forensic DNA profile analysis. Module 2 examines the problems and challenges encountered in extracting DNA and generating DNA profiles. It provides information on the methods and the best practices for DNA isolation from forensic biological samples and human remains like ancient DNA, DNA typing of skeletal remains and disast...
Companion to Music in the Age of the Catholic Monarchs
The Companion to Music in the Age of the Catholic Monarchs, edited by Tess Knighton, offers a major new study that deepens and enriches our understanding of the forms and functions of music that flourished in late medieval Spanish society. The fifteen essays, written by leading authorities in the field, present a synthesis based on recently discovered material that throws new light on different aspects of musical life during the reign of Ferdinand and Isabel (1474-1516): sacred and secular music-making in royal and aristocratic circles; the cathedral music environment; liturgy and power; musical connections with Rome, Portugal and the New World; theoretical and unwritten musical practices; women as patrons and performers; and the legacy of Jewish musical tradition. Contributors are Mercedes Castillo Ferreira, Giuseppe Fiorentino, Roberta Freund Schwartz, Eleazar Gutwirth, Tess Knighton, Kenneth Kreitner, Javier Marín López, Ascensión Mazuela-Anguita, Bernadette Nelson, Pilar Ramos López, Emilio Ros-Fábregas, Juan Ruiz Jiménez, Richard Sherr, Ronald Surtz, and Jane Whetnall.
From Tribute to Communal Sovereignty
From Tribute to Communal Sovereignty examines both continuity and change over the last five centuries for the indigenous peoples of central western Mexico, providing the first sweeping and comprehensive history of this important region in Mesoamerica. The continuities elucidated concern ancestral territorial claims that date back centuries and reflect the stable geographic locations occupied by core populations of indigenous language–speakers in or near their pre-Columbian territories since the Postclassical period, from the thirteenth to late fifteenth centuries. A common theme of this volume is the strong cohesive forces present, not only in the colonial construction of Christian village...
Pharmacogenomics and Personalized Medicine
Pharmacogenomics is one of the emerging approaches to precision medicine, tailoring drug selection and dosing to the patient’s genetic features. In recent years, several pharmacogenetic guidelines have been published by international scientific consortia, but the uptake in clinical practice is still poor. Many coordinated international efforts are ongoing in order to overcome the existing barriers to pharmacogenomic implementation. On the other hand, existing validated pharmacogenomic markers can explain only a minor part of the observed clinical variability in the therapeutic outcome. New investigational approaches are warranted, including a study of the pharmacogenomic role of the immune...
Nitric Oxide in Health and Disease
Nitric Oxide in Health and Disease: Therapeutic Applications in Cancer and Inflammatory Disorders presents updated information on the chemistry, signaling of newly derived therapeutic nitric oxide donors/inhibitors, and their complexes in liposomes or nanospheres in both pre-clinical and clinical activities. The book discusses many examples of research related to the application of novel therapeutic compounds that focus on a chemical—nitric oxide—and its applications that have been shown to exert significant therapeutic activities against various resistant cancers unresponsive to current treatments and different inflammatory diseases which continue to require novel treatments. This is a ...
DNA Fingerprinting: Advancements and Future Endeavors
This book describes the basics and various applications of DNA fingerprinting, including in actual case studies. The book is divided in four modules; Module 1: Basics of DNA Fingerprinting, Module 2: Applications of DNA Fingerprinting, Module 3: DNA Fingerprinting: Case Studies, and Module 4: Future of DNA Fingerprinting. Each module consists of 4 to 5 chapters, written by reputed researchers, academics and forensic scientists from around the globe. The respective chapters cover e.g. related fields, the tools and techniques used, various genotyping kits, real-world case studies, ancient DNA and wild life forensics, molecular diagnosis of human diseases, legal aspects, microbial forensics and...
Exploring Multilingualism and Multiscriptism in Written Artefacts
This book explores multilingualism and multiscriptism in a great variety of writing cultures, offering an in-depth analysis of how diverse languages and scripts seamlessly intertwine within written artefacts. Insights into scribal practices are particularly illuminating in that respect, especially when exploring artefacts originating from multicultural communities and regions where distinct writing traditions intersect. The influence of multilingualism and multiscriptism on these writing cultures becomes evident, with essays spanning various domains, from the mundane aspects of everyday life to the realms of scholarship and political propaganda. Scholars often relegate these phenomena, despi...
The Neurobiology, Physiology, and Psychology of Pain
The Neurobiology, Physiology and Psychology of Pain focuses on bettering readers' understanding of acute and chronic pain. Featuring chapters on neurotransmitters, pharmacology, and brain imaging, this volume discusses, in detail, the mechanisms of pain and experimental studies undertaken to better understand the pathways involved. The translational work in this area has applicability for neurologists, anesthesiologists, pharmacologists, and anyone working in the intersection of these areas. This volume is integral for anyone interested in the molecular underpinnings of pain at every level. - Provides comprehensive coverage on a broad range of topics related to the neuroscience of pain - Contains an abstract, key facts, a mini dictionary of terms, and summary points to aid in understanding in each chapter - Features chapters on molecular pathways, imaging and a deep look at behavior associated with the experience of pain - Contains unique topics that will help readers navigate key areas for research and further clinical recommendations
The Routledge Handbook of Mesoamerican Bioarchaeology
This volume brings together a range of contributors with different and hybrid academic backgrounds to explore, through bioarchaeology, the past human experience in the territories that span Mesoamerica. This handbook provides systematic bioarchaeological coverage of skeletal research in the ancient Mesoamericas. It offers an integrated collection of engrained, bioculturally embedded explorations of relevant and timely topics, such as population shifts, lifestyles, body concepts, beauty, gender, health, foodways, social inequality, and violence. The additional treatment of new methodologies, local cultural settings, and theoretic frames rounds out the scope of this handbook. The selection of 36 chapter contributions invites readers to engage with the human condition in ancient and not-so-ancient Mesoamerica and beyond. The Routledge Handbook of Mesoamerican Bioarchaeology is addressed to an audience of Mesoamericanists, students, and researchers in bioarchaeology and related fields. It serves as a comprehensive reference for courses on Mesoamerica, bioarchaeology, and Native American studies.
