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This eighth volume in the series Methods of Cancer Diagnosis, Therapy, and Prognosis discusses in detail the classification of the CNS tumors as well as brain tumor imaging. Scientists and Clinicians have contributed state of the art chapters on their respective areas of expertise, providing the reader a whole field view of the CNS tumors and brain tumor imaging in Europe. This fully illustrated volume: Explains the genetics of malignant brain tumors and gene amplification using quantitative-PCR; Presents a large number of standard and new imaging modalities, including magnetic resonance imaging, functional magnetic resonance imaging, diffusion tensor imaging, amide proton transfer imaging, ...
This volume sets a basis for effective translational research. Authored by experts in the field of translational stroke research, each chapter specifically addresses one or more components of preclinical stroke research. The emphasis is placed on target identification and drug development using state-of-the-art in vitro and in vivo assays, in combination with in vitro toxicology assays, AMDE and clinical design.
Olli Tenovuo is consultant and member of SAB for NeuroTrauma Sciences LLC (Georgia, USA) and ABCDx SA (Geneva, Switzerland). Jean-Charles Sanchez has a research grant to disclose from ABCDx SA, (Geneva, Switzerland). Damir Janigro is the CEO of FloTBI Inc. (Cleveland, USA), a company interested in biomarkers of neurological diseases.
A cutting-edge synthesis of science and practice, this book covers everything from sports-related concussions to less common types of mild traumatic brain injury (mTBI) and related complications. Preeminent authorities review what is known about mTBI in childhood and adolescence—including its biomechanics, pathophysiology, and neurological and neurobehavioral outcomes—and showcase evidence-based clinical evaluation tools and management strategies. Challenging areas such as evaluating complicated mTBI and treating persistent problems after injury are discussed in detail. Also addressed are forensic issues, injury in very early childhood, and other special-interest topics.
A concise introductory textbook on the development of the nervous system This textbook offers a concise introduction to the exciting field of developmental neuroscience, a discipline concerned with the mechanisms by which complex nervous systems emerge during embryonic growth. Bridging the divide between basic and clinical research, it captures the extraordinary progress that has been achieved in the field. It provides an opportunity for students to apply and extend what they have learned in their introductory biology courses while also directing them to the primary literature. This accessible textbook is unique in that it takes an in-depth look at a small number of key model systems and sig...
In this book, leading world authorities on brain edema and neurological disorders/injuries and experts in preconditioning join forces to discuss the latest progress in basic sciences, translational research, and clinical management strategies relating to these conditions. The range of topics covered is wide, including microglia, energy metabolism, trace metals and ion channels, vascular biology, cellular treatment, hemorrhagic stroke, novel technological advances, anesthesia and medical gases, pediatric brain edema, neuroimaging, behavioral assessment, clinical trials, peripheral to central signaling pathways, preconditioning translation, and animal models for preconditioning and brain edema research. The book comprises presentations from Brain Edema 2014, the joint meeting of the 16th International Conference on Brain Edema and Cellular Injury and the 3rd Symposium on Preconditioning for Neurological Disorders, held in Los Angeles on September 27–30, 2014.
Brain Edema: From Molecular Mechanisms to Clinical Practice brings together the most widely recognized experts in experimental and clinical brain edema research to review the current knowledge gathered on the molecular and cellular pathophysiology and clinical management of brain edema. This timely book also discusses future directions of research and treatment. Brain edema is an integral and acutely life-threatening part of the pathophysiology of multiple cerebral and non-cerebral disorders, including traumatic brain injury, cerebral ischemia, brain tumors, cardiac arrest, altitude sickness and liver failure. Affecting millions worldwide, research over the past few years has shown that a pl...