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The 'Civilising Mission' of Portuguese Colonialism, 1870-1930
This book provides an historical, critical analysis of the doctrine of 'civilising mission' in Portuguese colonialism in the crucial period from 1870 to 1930. Exploring international contexts and transnational connections, this 'civilising mission' is analysed and assessed by examining the employment and distribution of African manpower.
Colposcopy and Treatment of Cervical Precancer [OP]
This colposcopy manual was developed in the context of the cervical cancer screening research studies of the International Agency for Research on Cancer (IARC) and the related technical support provided to national programs. It is thus a highly comprehensive manual, both for the training of new colposcopists and for the continuing education and reorientation of those who are more experienced. This manual offers a valuable learning resource, incorporating recent developments in the understanding of the etiology and pathogenesis of cervical intraepithelial neoplasia (CIN), as well as in colposcopy and cervical pathology. Expertise in performing satisfactory, safe, and accurate colposcopic examinations requires high competence in the technical, interpretive, and cognitive aspects, and the capability to develop pragmatic and effective management plans and treatment. This comprehensive and concise manual covers all these aspects and serves as a useful handbook for acquiring the necessary skills for the visual recognition and interpretation of colposcopic findings and for developing the personal and professional attributes required for competence in colposcopy.
Preventive Oncology for the Gynecologist
This book explores all aspects of preventive oncology of the female genital tract and provides readers with detailed insights on the topic. Preventive oncology has long been recognized as a pressing need, though formally few steps have been taken to actively promote it. The book’s respective chapters holistically cover the concept of cancer prevention for the female genital tract & breast. In addition, it explains the evidence-based value of each screening modality, and the rationale behind the recommended screening guidelines. In closing, the book highlights a wealth of recent evidence-based literature, making it a highly informative resource that will significantly broaden readers’ understanding of preventive oncology.
Textiles, Identity and Innovation: In Touch
D_Tex is proposed as a hub around which it is possible to look at textiles in their different forms, in order to better understand, study, adapt and project them for the future. It is intended to build a flow of ideas and concepts so that participants can arrive at new ideas and concepts and work them in their own way, adapting them to their objectives and research. D_Tex is intended as a space for sharing and building knowledge around textile material in order to propose new understandings and explorations. Present in all areas of knowledge, the textile material bets on renewed social readings and its evolutions to constantly reinvent itself and enable innovative cultural and aesthetic dime...
Comprehensive Cervical Cancer Control
Most women who die from cervical cancer, particularly in developing countries, are in the prime of their life. They may be raising children, caring for their family, and contributing to the social and economic life of their town or village. Their death is both a personal tragedy, and a sad and unnecessary loss to their family and their community. Unnecessary, because there is compelling evidence, as this Guide makes clear, that cervical cancer is one of the most preventable and treatable forms of cancer, as long as it is detected early and managed effectively. Unfortunately, the majority of women in developing countries still do not have access to cervical cancer prevention programmes. The consequence is that, often, cervical cancer is not detected until it is too late to be cured. An urgent effort is required if this situation is to be corrected. This Guide is intended to help those responsible for providing services aimed at reducing the burden posed by cervical cancer for women, communities and health systems. It focuses on the knowledge and skills needed by health care providers, at different levels of care.
Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy
Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy discusses recently developed treatments based on molecular targets which are genetically altered in cancer cells and are essential for tumor development and survival. Considerable research effort has been devoted to the development of targeted drugs that inhibit the action of pathogenic kinases, and clinical studies performed so far have validated the positive effects of kinase inhibitors for cancer treatment. Each chapter discusses a molecular target, such as ALK2, ATR, CK, Src-Abl, EGFR, Fyn-Blk-Lyn, IGFs, and PAK1. The book's chapters are written by experts who actively work on the targets to help readers fully underst...
HPV and Cancer
“HPV and Cancer” is a concise read that covers all aspects of the Human Papilloma Virus as it relates to human cancers. While written by professionals, it design to be understandable by those that are not in the field, yet it has the technical details that professionals want to stay abreast of this changing field. The book starts out the history of HPV and progresses into the molecular biology of the virus and our current understand of the structure and functions of the proteins and genes it encodes. We then look at the dynamic trends of this infectious agent in the human population, how it interacts with human cells, and the role it plays with other organisms to produce both benign and malignant tumors. Lastly, there is a discussion about a new vaccine for HPV and the hopes that are held by many to change the trends with this virus and the associated cancers it produces.
Protein-Protein Interactions
The second volume of the book-Protein-Protein Interactions (PPIs) provides an overview of various protein-protein interactions (PPIs) that are involved in various human diseases including cancer, neurodegenerative diseases, immune diseases, and inflammation. It summarizes the structure and ligand-based drug designing approaches for the discovery of small molecules that can inhibit PPIs in these diseases. The book discusses different computational and experimental tools that are used to determine the anomalous interactions underlying the diseases. Lastly, it also reviews the classical interactions between pathogens and hosts that are responsible for the pathophysiology of infectious diseases.
