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Induction Chemotherapy
This book presents the full range of management techniques and practices used in induction chemotherapy – both systemic and locoregional - by experienced international groups within one accessible volume. It provides the latest information on the pioneering and cutting-edge practices employed in different institutions and documents the advantages of integrated treatment schedules. All those responsible for treating patients with locally advanced cancers may find new, interesting aspects of locoregional cancer management and will find this book to be an invaluable source of up-to-date information. Throughout the world, induction chemotherapy is being used as part of an integrated plan of ma...
B Cell Receptor Signaling
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Digital Human Modeling
The emerging information technologies have enabled new human patterns ranging from physiological interactions to psychological interactions. Perhaps the best example is the rapid ‘evolution’ of our thumbs from simply holding to controlling mobile devices in just a few years recently. Taking the medical field as an example, the fast-growing technologies such as pill cameras, implantable devices, robotic surgeries, and virtual reality training methods will change the way we live and work. Human Algorithms aim to model human forms, interactions, and dynamics in this new context. Human Algorithms are engineering methods that are beyond theories. They intend to push the envelopes of multi-phy...
Membrane Biogenesis
Scientific reviews are now of two complementary types: short, very up-to-date articles, as are found in the Trends series, and the more traditional longer re views, which are more comprehensive but take longer to publish. The Subcellu lar Biochemistry series belongs to the latter category where a number of reviews on a broad topic are collected together in the one volume. It has been the aim of this volume to summarize the present state of knowledge of membrane assembly. It is appreciated that some relevant topics have not been included, and an editor's selection is restricted by the many calls on potential authors who are unable to meet all requests made to them. The absence of a discussion of the roles of lipids is," however, a reflection of the fact that a recent volume in this series, edited by Dr. H. 1. Hilderson, has been devoted to this subject (Vol. 16, Intracellular Transfer of Lipid Molecules), and readers are recommended to this source.
The Dark Side of Neuro-Intervention
Neuro-intervention is widely believed to be one of medicine’s most exciting specialties, given that it is growing, dynamic and often rewarding in countless ways to both practitioners and patients. However, it can be a source of misfortune to recipients and its providers alike, in more ways than many of us realize or care to admit. This book shows that some problems associated with the field are not solely a product of outlying circumstances or individuals, but are, rather, systemic, insidious and ubiquitous issues affecting research, education, and publications.
Minimally Invasive Thoracic and Cardiac Surgery
It is now 20 years since thoracoscopic surgery first entered everyday hospital practice, revolutionizing surgery and offering major benefits to patients. The intervening years have witnessed rapid progress, with the development of a variety of specialized techniques and equipment. This superbly illustrated book provides authoritative and comprehensive descriptions of the various minimally invasive techniques that are currently employed in thoracic and cardiac surgery. A wide range of thoracoscopic procedures are explained and discussed, and detailed attention is also paid to robotic and robot-assisted surgical techniques. Throughout, the emphasis is on clear description of procedures and identification of practical aspects of relevance in surgical practice. The authors are some of the world’s most experienced thoracic and cardiac surgeons, and many of them have contributed greatly to the exploration and development of the field.
Atrial Fibrillation: New Insights for the Healthcare Professional: 2011 Edition
Atrial Fibrillation: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Atrial Fibrillation. The editors have built Atrial Fibrillation: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Atrial Fibrillation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Atrial Fibrillation: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Harm Reduction
From addictions treatment pioneer G. Alan Marlatt and associates, this is the authoritative work on harm reduction: its principles, strategies, and practical applications. Contributors review programs that have been developed and tested for a range of high-risk behaviors, including problem drinking, tobacco use, illicit drug use, and risky sexual behavior. Flexible, tailored, culturally competent treatment approaches are described for marginalized and underserved communities. The volume also explores philosophical and policy-related debates surrounding this growing movement. New to This Edition*Reflects significant advances in research and clinical practice.*Chapters on the current status of the field, applications to psychotherapy, and treatment of dual disorders.*Chapters on additional populations (adolescent drinkers and Hispanic/Latino and Asian American substance users) and an additional substance (cannabis).
Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new mate...
Nutrition and Diet in Health
Nutrition and diet play a crucial role in sustaining good health throughout human lives. Food provides us with essential nutrients involved in many physiological activities and biological processes in the body including growth and development, metabolism, immune function, and overall well-being. Nutrition and Diet in Health: Principles and Applications reviews and discusses the issues related to the roles of nutrition and diet in human health and diseases. The book contains two sections – one section features principles, the other, covers applications. Part I provides information on sustainable use of nutrition and diets in health and diseases; advanced biotechnological approaches to impro...
