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Myc as a Disease Target Beyond Cancer
Myc is a pleiotropic transcription factor fundamental for many cellular processes. It is an infamous and highly-studied oncogene, with around 10,000 articles published in the last decade. The majority of these link it to cancer. The focus on Myc as a hot target in cancer has led to immense efforts – from academia through to pharmaceutical companies – being directed towards finding a Myc inhibitor. Not surprisingly, given its fundamental nature in many physiological processes, Myc has also been linked to a large variety of pathologies other than cancer. The growing efforts to develop Myc inhibitors as cancer therapies will have important implications for the treatment of these diseases to...
A Quest for the Physical Reality of Time
Some scientists believe that time is physical such as matter and other scientists believe that time is an imagination such as the numbers 1, 2, and 3. Did we invent time or was time here in the universe before we came to existence? This book answers this question. This book also tells the stories of my encounters of physics Nobel laureates such as I.I Rabi, T.D. Lee, Murray Gell-Mann, James Rainwater. and more.
The Biology of Cancer
Thoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world.The Biology of Cancer is a textbook for students studying the molecular and cellula
In Defense of Processed Food
An iconoclastic celebration of canned, packaged, and preserved foods. By turns a scientific, feminist, and economic critique, this book gleefully attacks received wisdom about the dangers of processed food. Anastacia Marx de Salcedo argues that, in fact, most processed foods are relatively healthy and that their consumption is an undisputed boon to women’s equality—since the burdens of cooking disproportionately fall on women. In de Salcedo’s account, processed foods take too much blame for the negative effects of modern sedentary life, and alternative food systems are doomed to economic dysfunction. Ultimately, de Salcedo embraces the preserved foods in her pantry and encourages the reader to do the same.
Pandora's Box
This book is about the coronavirus and the pandemic it spawned, and what this outbreak means for future pandemics. It analyses the official response and sees where improvements can be made, for example, the World Health Organization waited till March to designate the coronavirus a pandemic and a full year before confirming its airborne transmission. The book looks at the specific nature of the virus, its origins and how it was transmitted, why it was so deadly to predisposed individuals, how it compares to previous pandemics, what measures were taken mitigate the disease and how to protect ourselves against it in future. The book also looks into the wider implications of the pandemic and its...
Journal of the House of Representatives of the United States
Some vols. include supplemental journals of "such proceedings of the sessions, as, during the time they were depending, were ordered to be kept secret, and respecting which the injunction of secrecy was afterwards taken off by the order of the House."
Tumor Suppressor Genes
It has become clear that tumors result from excessive cell proliferation and a corresponding reduction in cell death caused by the successive accumulation of mutations in key regulatory target genes over time. During the 1980s, a number of oncogenes were characterized, whereas from the 1990s to the present, the emp- sis has shifted to tumor suppressor genes (TSGs). It has become clear that oncogenes and TSGs function in the same pathways, providing positive and negative growth regulatory activities. The signaling pathways controlled by these genes involve virtually every process in cell biology, including nuclear events, cell cycle, cell death, cytoskeletal, cell membrane, angiogenesis, and ...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
