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Mitogen Activated Protein Kinases
Mitogen-activated protein kinase (MAPK) pathways are evolutionarily conserved in all eukaryotes and allow cells to respond to changes in the physical and chemical properties of the environment and to produce an appropriate response by altering many cellular functions. MAPKs are among the most intensively studied signal transduction systems. MAPK research is a very dynamic field in which new perspectives are continuously opening to the scientific community. Importantly, many MAPK inhibitors have been developed during the last years and are currently being tested in preclinical and clinical assays for inflammatory diseases and cancer treatment. In this research topic, we have gathered 14 paper...
The Tangled Tree
In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology affect our understanding of evolution and life’s history. In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important; we now know that roughly eight perc...
Current Sociology
Vols. 1-4 contain v. 1-4 of International bibliography of sociology.
17th International Conference on Soft Computing Models in Industrial and Environmental Applications (SOCO 2022)
This book contains accepted papers presented at SOCO 2022 conference held in the beautiful and historic city of Salamanca (Spain), in September 2022. Soft computing represents a collection or set of computational techniques in machine learning, computer science, and some engineering disciplines, which investigate, simulate, and analyze very complex issues and phenomena. After a thorough peer-review process, the 17th SOCO 2022 International Program Committee selected 64 papers which are published in these conference proceedings and represent an acceptance rate of 60%. In this relevant edition, a particular emphasis was put on the organization of special sessions. Seven special sessions were o...
Latin America and Refugee Protection
Looking at refugee protection in Latin America, this landmark edited collection assesses what the region has achieved in recent years. It analyses Latin America’s main documents in refugee protection, evaluates the particular aspects of different regimes, and reviews their emergence, development and effect, to develop understanding of refugee protection in the region. Drawing from multidisciplinary texts from both leading academics and practitioners, this comprehensive, innovative and highly topical book adopts an analytical framework to understand and improve Latin America’s protection of refugees.
La teología en España 1959-2009
El cristianismo histórico es decisión de razón, confesión de fe y praxis de vida. En los tres casos incluye la inteligencia que reclama sentido, la voluntad que demanda motivos y el corazón que necesita potencias sustentadoras para vivir. La teología es el órgano que en la Iglesia tiene como misión indagar las razones que abren la inteligencia a la fe a la vez que las razones que llevan la fe a la inteligencia; y ambas al amor y a la praxis. Una inteligencia que siempre es a la vez abertura trascendental al Misterio y atenimiento riguroso a la historia. Este libro es una meditación sobre la teología y la Iglesia en España, con la mirada puesta en Europa como trasfondo permanente, en la medida en que estas cuatro realidades están implicadas unas en otras y se han condicionado durante los últimos cincuenta años.
The Metabolic Syndrome at the Beginning of the XXI Century
El síndrome metabólico es uno de los retos más intrigantes y fascinantes de la medicina contemporánea. Se trata de una patología en la que confluyen problemas de distintas áreas de la medicina: diferentes grados de hipertensión, acumulación de grasa, insulinoresistencia, estados protrombótico y proinflamatorio, todos juntos en la misma persona. Esta concurrencia de factores hace que la persona tenga un riesgo mucho mayor de sufrir enfermedad cardiovascular o diabetes mellitus tipo 2, que lo que la suma de los factores individuales supondría. Se trata de una "enfermedad" nueva, que ha llegado a ser un problema de salud pública muy importante en las sociedades desarrolladas y cuya r...
