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The diversity of the chapters presented in this volume illustrates not only the many applications of lasers, but also the fact that, in many cases, these are not new uses of lasers, but rather improvements of laser techniques already widely accepted in both research and clinical situations. Biological reactions to some special aspects of laser exposure continue to show new effects, which have implications for the ever-present topic of laser safety. Such biological reactions are included in fields of research which depend on properties of electromagnetic radiation exposure only possible with lasers, for example, the short pulses necessary for the temperature-jump experiments reviewed by Reiss...
This book presents an analysis of limits in perception from the vantage point of the physicist, the engineer, the psychophysicist, the psychologist and the theorist. Limits in perception find their causal explanation at many logically and/or physically different levels. Some of the most fundamental bottlenecks are due to the quantum mechanical and atomistic structure of the microworld. Other simple constraints are due to the material constitution of sensory organs. For instance, the fact that the eye is predominantly composed of water limits both the optical quality and the available spectral window. The engineer uses knowledge on such limits to design equipment that optimizes human performa...
" ... And the evening and the morning were the third day ... And God made two great lights; the greater light to rule the day and the lesser light to rule the night ... And the evening and the morning were the fourth day." The First Book of Moses, called Genesis (1: 13,16,19). There was daytime and nighttime before there was a sun or a moon. An interesting thought: How long were each of those first three days? Without a sun to reckon its length, a day could have been longer or shorter than 24 hours. Animals, says Genesis, appeared on the fifth day and by that time the sun and moon were illuminating the earth, presumably in cyclic fashion and with a period of 24 hours. A good thing, too, as r...
This book emphasizes concepts and methods for solving problems that occur through the interaction of the eyes and vision of people with their environment. Student clinicians will learn to assess their patient's visual tasks, visual environments, and visual performance needs in order to provide quality eye care.
This, the 148th volume of the Handbook of Experimental Pharmacology series, focuses on the very core of pharmacology, namely receptor theory. It is fitting that the originator of receptor pharmacology, A. J. CLARK, authored the fourth volume of this series 63 years ago. In that volume CLARK further developed his version of receptor theory first described four years earlier in his classic book The Mode of Action of Drugs. An examination of the topics covered in volume 4 reveals a striking similarity to the topics covered in this present volume; pharmacologists today are still as interested in unlocking the secrets of dose-response relationships to reveal the biological and che mical basis of ...
Born in Italy in 1891, Andy Varipapa immigrated to the United States in 1903, uneducated and unable to speak English. Equipped with little more than athletic ability, the will to succeed, and a healthy dose of self-confidence, he became bowling's first superstar. In the 1940s and 1950s, Varipapa was the world's most famous bowler. For more than 50 years, he dazzled fans with an array of never-before-seen trick shots in person, on movie screens, and on television. Varipapa was not only a performer but one of the greatest bowlers ever. He won the prestigious BPAA All-Star tournament in 1946, silencing critics who claimed he was just an entertainer. And he did so at age 55, long past most bowle...
Providing a comprehensive review of reactions of oxidation for different classes of organic compounds and polymers, and biological processes mediated by free radicals, Oxidation and Antioxidants in Organic Chemistry and Biology puts the data and bibliographical information you need into one easy-to-use resource. You will find up-to-date information
Recent publications have addressed specific aspects of the endothelins, such as their roles in disease or the importance of endothelin receptors. However, in this book the entire field of endothelins is covered. This includes the pathways of endothelin production and their regulation, the local and systemic actions of endothelins, receptors for the endothelins and the signalling pathways employed, and the involvement of endothelins in a range of diseases. Attention is also paid to the development through chemistry, pharmacology and toxicology of endothelin antagonists and endothelin-converting enzyme inhibitors, with mention of all the important members of these drug classes. This leads to well-rounded discussions of the potential therapeutic benefit of endothelin inhibitors.