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Isocucurbitacin B inhibits glioma growth through PI3K/AKT pathways and increases glioma sensitivity to TMZ by inhibiting hsa-mir-1286a
Aim: Glioma accounts for 81% of all cancers of the nervous system cancers and presents one of the most drug-resistant malignancies, resulting in a relatively high mortality rate. Despite extensive efforts, the complete treatment options for glioma remain elusive. The effect of isocucurbitacin B (isocuB), a natural compound extracted from melon pedicels, on glioma has not been investigated. This study aims to investigate the inhibitory effect of isocuB on glioma and elucidate its underlying mechanisms, with the objective of developing it as a potential therapeutic agent for glioma. Methods: We used network pharmacology and bioinformatics analysis to predict potential targets and associated pa...
2014 International Conference on Biological Engineering and Biomedical
The BEAB 2014 provides a high level international forum to bring together industry professionals, academics, and individuals from institutions, industrials and government agencies to exchange information, share achievements, and discuss the advancement in the fields of Biological Engineering, Biomedical Engineering, Biomedical Material and application, and discussed the practical challenges encountered and the solution adopted. The BEAB2014 tends to collect the latest research results and applications on Biological Engineering, Biomedical Engineering, Biomedical Material and application. It includes a selection of 56 papers from 215 papers submitted to the conference from universities and in...
The Right To Be Counted
In the last 30 years, Delhi, the capital of India, has displaced over 1.5 million poor people. Resettlement and welfare services are available-but exclusively so, as the city deems much of the population ineligible for civic benefits. The Right to Be Counted examines how Delhi's urban poor, in an effort to gain visibility from the local state, incrementally stake their claims to a house and life in the city. Contributing to debates about the contradictions of state governmentality and the citizenship projects of the poor in Delhi, this book explores social suffering, logistics, and the logic of political mobilizations that emanate from processes of displacement and resettlement. Sanjeev Rout...
Neuroscientific Research for Management of Dementia
The articles in this eBook are divided into three main chapters. Chapter 1 focuses on the role of specific proteins in the pathological processes of neurodegeneration, specifically Alzheimer's disease. Chapter 2 describes novel candidates and risk factors for the diagnosis of Alzheimer's disease. Chapter 3 targets various therapeutic interventions from pharmacological targets to cognitive function. This eBook thus provides an overall overview of the latest research in understanding mechanisms leading to the development of Alzheimer's disease, diagnosis, and therapeutic interventions.
Histoire des missions chrétiennes
Passe en revue les différents moments de l'expansion du christianisme en soulignant les divers courants d'évangélisation issus tant du catholicisme, de l'orthodoxie, que du protestantisme. Met l'accent sur le fort développement de l'Eglise dans l'Est de l'Inde, comme dans la Chine du VIIe siècle, sur le renouveau missionnaire au XIXe siècle et les rapports complexes entre colonisation et mission.
The Book of Chinese Medicine, Volume 2
This second volume offers numerous approaches to using Chinese medicine for the prevention and treatment of various diseases in medical practice. It brings the concepts and theories learned in the first volume and applies them in clinical settings with real patient examples. It goes over the four natures and five flavors of herbal drugs, and covers the different techniques of acupuncture. The book considers how the advancements in modern technology have shaped Traditional Chinese Medicine (TCM), and discusses the revolutionary innovations that are occurring in the Chinese medicine industry today and how they will shape the future.
