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Molecular Mechanisms of Programmed Cell Death
  • Language: en
  • Pages: 229

Molecular Mechanisms of Programmed Cell Death

The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner, H. Robert Horvitz, and John E. Sulston for their seminal discoveries concerning "genetic regulation of organ development and programmed cell death." This clearly marked the prime importance of understanding the molecular mechanisms controlling cell death. The 1 st International Symposium on Programmed Cell Death was held in the Shanghai Science Center of the Chinese Academy of Sciences on September 8-12, 1996. A number of key issues in apoptosis were discussed at the meeting, and progress in major areas of apopto sis research was summarized by expert participants at the meeting and published by Plenum Publishing Corporation as a book entitled Programmed Cell Death. In the last six years, we have witnessed a real explosion in our knowledge on how cells undergo apoptosis, thereby participating in various developmental and pathophysiological processes. At this ever exciting time, we organized the 2nd International Symposium on Programmed Cell Death.

Current Topics in Developmental Biology
  • Language: en
  • Pages: 259

Current Topics in Developmental Biology

This Series provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. This year marks a major milestone for the Series as it completes its thirtieth year of publication, making it the longest-running forum for contemporary issues in developmental biology.

Cumulative Subject Index
  • Language: en
  • Pages: 225

Cumulative Subject Index

This Series provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The Series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.

Cell Death
  • Language: en
  • Pages: 280

Cell Death

Beginning from centuries of anecdotal descriptions of cell death, such as those on the development of the midwife toad in 1842 by Carl Vogt, to modern-day investigations of cell death as a biological discipline, it has become accepted that cell death in multicellular organisms is a normal part of life. This book provides a comprehensive view of cell death, from its mechanisms of initiation and execution, to its implication in human disease and therapy. Physiological cell death plays critical roles in almost all aspects of biology, and the book details its roles in lymphocyte homeostasis, neuronal function, metabolism, and the DNA damage response. When physiological cell death goes awry, dise...

The Molecular Basis of Programmed Cell Death and Neuroinflammation in Neurodegenerative Diseases
  • Language: en
  • Pages: 138

The Molecular Basis of Programmed Cell Death and Neuroinflammation in Neurodegenerative Diseases

Age-related neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuroinflammation as well as neuronal degeneration. Apoptosis, necrosis, and autophagy are all types of programmed cell death that are morphologically distinct from one another. Over the last decade, extensive research has been conducted on necroptosis, resulting in a better understanding of its molecular underpinnings and role in neurodegenerative diseases. A later study investigates the processes of apoptosis and necroptosis, as well as their roles in the activation of inflammatory immune responses. Although there is a distinct mode of cell death with distinct morphol...

International Review of Cell and Molecular Biology
  • Language: en
  • Pages: 255

International Review of Cell and Molecular Biology

International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2009: 6.088. Authored by some of the foremost scientists in the field Provides up-to-date information and directions for future research Valuable reference material for advanced undergraduates, graduate students and professional scientists

Meiosis and Gametogenesis
  • Language: en
  • Pages: 447

Meiosis and Gametogenesis

In spite of the fact that the process of meiosis is fundamental to inheritance, surprisingly little is understood about how it actually occurs. There has recently been a flurry of research activity in this area and this volume summarizes the advances coming from this work. All authors are recognized and respected research scientists at the forefront of research in meiosis. Of particular interest is the emphasis in this volume on meiosis in the context of gametogenesis in higher eukaryotic organisms, backed up by chapters on meiotic mechanisms in other model organisms. The focus is on modern molecular and cytological techniques and how these have elucidated fundamental mechanisms of meiosis. ...

Computer Supported Cooperative Work and Social Computing
  • Language: en
  • Pages: 553

Computer Supported Cooperative Work and Social Computing

This two-volume set constitutes the refereed proceedings of the 17th CCF Conference on Computer Supported Cooperative Work and Social Computing, ChineseCSCW 2022 held in Taiyuan, China, during November 25–27, 2022. The 60 full papers and 30 short papers included in this two-volume set were carefully reviewed and selected from 211 submissions. They were organized in topical sections as follows: answer set programming; Social Media and Online Communities, Collaborative Mechanisms, Models, Approaches, Algorithms and Systems; Crowd Intelligence and Crowd Cooperative Computing; Cooperative Evolutionary Computation and Human-like Intelligent Collaboration; Domain-Specific Collaborative Applications.

Environmental Health Perspectives
  • Language: en
  • Pages: 452

Environmental Health Perspectives

  • Type: Book
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  • Published: 1996
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  • Publisher: Unknown

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Proteases in Human Diseases
  • Language: en
  • Pages: 516

Proteases in Human Diseases

  • Type: Book
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  • Published: 2017-07-13
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  • Publisher: Springer

This book bridges the gap between fundamental research and biomedical and pharmacological applications on proteases. It represents a comprehensive overview of the multifaceted field of proteases in cellular environment and highlights the recently elucidated functions of complex proteolytic systems in different diseases. Several established investigators have elucidated the crucial role of proteases in biological processes, including how proteolytic function and regulation can be combined to develop new strategies of therapeutic interventions. Proteases form one of the largest and most diverse families of enzymes known. It is now clear that proteases are involved in every aspect of life funct...