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Novel Immune Markers and Predictive Models for Immunotherapy and Prognosis in Breast and Gynecological Cancers
  • Language: en
  • Pages: 203

Novel Immune Markers and Predictive Models for Immunotherapy and Prognosis in Breast and Gynecological Cancers

Precision medicine is an emerging practice by which clinicians aim to deliver a personalized treatment program to affected patients based on information gained from their individual clinical and biological profiles. In the context of precise cancer immunotherapy, multi-omics, high-throughput sequencing, big data, and other approaches serve to screen new predictive factors for immunotherapy response and prognosis in cancer patients.

The Ancient Origins of Consciousness
  • Language: en
  • Pages: 387

The Ancient Origins of Consciousness

  • Type: Book
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  • Published: 2017-09-08
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  • Publisher: MIT Press

How consciousness appeared much earlier in evolutionary history than is commonly assumed, and why all vertebrates and perhaps even some invertebrates are conscious. How is consciousness created? When did it first appear on Earth, and how did it evolve? What constitutes consciousness, and which animals can be said to be sentient? In this book, Todd Feinberg and Jon Mallatt draw on recent scientific findings to answer these questions—and to tackle the most fundamental question about the nature of consciousness: how does the material brain create subjective experience? After assembling a list of the biological and neurobiological features that seem responsible for consciousness, and consideri...

A Hegemonic Form of Transfer Pricing
  • Language: en

A Hegemonic Form of Transfer Pricing

  • Type: Book
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  • Published: 2020
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  • Publisher: Unknown

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Re-living the City
  • Language: en
  • Pages: 673

Re-living the City

This richly illustrated book presents the exhibits and curatorial visions of the 2015 Shenzhen Biennale of Architecture and Urbanism (UABB), organized around the theme, Re-Living the City. It highlights the contributions of dozens of international architects, designers and artists, and offers 12 probing, original essays. The projects and essays of UABB 2015, Re-Living the City, criticize the status quo of architecture and urbanism, but they also resist the false dream of designing a perfect city from scratch. Instead, they portray the city as the incremental product of its inhabitants and designers, who provisionally make and remake its fabric through various means at their disposal. Urbaniz...

Gallstones
  • Language: en
  • Pages: 616

Gallstones

This book, the proceedings of the Falk Syposium No. 139 on "Gallstones: Pathogenesis and Treatment", held in Freiburg, Germany, on January 15-16, 2004, reflects the tremendous advances in the field of biliary diseases both at the genetic and cellular as well as the clinical levels. In industrialized countries, gallstones are a frequent clinical entity with a prevalence of 10-15%. In clinical practice one can differentiate between cholesterol stones, black pigment stones and brown pigment stones. 80-90% of gallbladder stones are cholesterol stones, 10--20% are black pigment stones. The prevalence of cholesterol stones increases with age and in Europe in the 70+ age group reaches about 20% in ...

The Potential Effects and Mechanisms of Chinese Traditional Medicine on Bone Homeostasis and Remodeling
  • Language: en
  • Pages: 156

The Potential Effects and Mechanisms of Chinese Traditional Medicine on Bone Homeostasis and Remodeling

Osteoporosis is a systemic skeletal disease, strongly affecting postmenopausal women and characterized by an increased risk of bone fragility and a decrease in bone mass. Bone homeostasis requires a balance between bone-forming osteoblasts and bone-resorbing osteoclasts. When this balance is impaired, normal bone remodelling cannot keep bone mass stable, leading to osteopenia and osteoporosis. About 30–50% of all women in the world suffer from fractures due to osteoporosis throughout their lives. The treatments include improving metabolic abnormalities through complementary and alternative therapies, drug application and surgical therapy for the management of overweight, obesity and hormone metabolism disorder. Chinese traditional medicine has been increasingly considered as an effective therapy for osteoporosis. A series of formulae, herbs and natural products have been indicated for their effects in the prevention and treatment of osteoporosis, such as Liu-Wei-Di-Huang Wan (formula), Morindae Officinalis Radix (herb), Longspur epimedium glycoside (natural product). However, the mechanisms of action remain largely unexplored.

11
  • Language: en
  • Pages: 392

11

This section of the Handbook of Zoology is intended as a comprehensive and exhaustive account of the biology of the taxa Gastrotricha, Nematoda, Nematomorpha, Priapulida, Kinorhyncha, Loricifera, Gnathostomulida, Micrognathozoa, Rotifera, Seisonida and Acanthocephala, covering all relevant topics such as morphology, ecology, phylogeny and diversity. The series is intended to be a detailed and up-to-date account of these taxa. As was the case with the first edition, the Handbook is intended to serve as a reliable resource for decades. Many of the taxa of this volume are comparatively unknown to many biologists, despite their diversity and importance for example in meiofaunal communities (Gast...

Rare Earth
  • Language: en
  • Pages: 376

Rare Earth

What determines whether complex life will arise on a planet, or even any life at all? Questions such as these are investigated in this groundbreaking book. In doing so, the authors synthesize information from astronomy, biology, and paleontology, and apply it to what we know about the rise of life on Earth and to what could possibly happen elsewhere in the universe. Everyone who has been thrilled by the recent discoveries of extrasolar planets and the indications of life on Mars and the Jovian moon Europa will be fascinated by Rare Earth, and its implications for those who look to the heavens for companionship.

Advances in Cognitive Neurodynamics (V)
  • Language: en
  • Pages: 809

Advances in Cognitive Neurodynamics (V)

  • Type: Book
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  • Published: 2016-01-29
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  • Publisher: Springer

This proceedings contains articles submitted to the fifth International Conference on Cognitive Neurodynamics (ICCN2015). In ICCN2015, twelve invited plenary lectures were presented by the leading scientists in their respective research fields. More than 15 mini-symposiums are organized by specialists with topics covering: motor control and learning, dynamic coding in distributed neural circuits, dynamics of firing patterns and synchronization in neuronal systems, information and signal processing techniques in neurotechnology, neural oscillations and synaptic plasticity in the hippocampus, new perspective on model-based vs. model-free brain process, neural mechanisms of internal switching, neuroinformation computation, neural model and dynamics, imaging human cognitive networks, neuroinformatics, neuroergonomics & neuroengineering, dynamic brain for communication, visual information processing and functional imaging and neural mechanisms of language processing. All articles are peer-reviewed. The ICCN is a series conference held every two years since 2007.

Research & Exploration
  • Language: en
  • Pages: 470

Research & Exploration

  • Type: Book
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  • Published: 1991
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  • Publisher: Unknown

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