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The Emperor of All Maladies
Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with...
The Truth in Small Doses
A decade ago Leaf, a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public's immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress-- brilliant young scientists-- are now abandoning the search for a cure.
Drug Discovery
Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design. Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contribut...
The Laboratory of Progress
The Laboratory of Progress: Switzerland in the 19th Century tells the improbable story of how a small, backward, mountainous agricultural country with almost no raw materials became an industrial powerhouse, a hub of innovation, a touristic mecca and a pioneer in transportation – all in the course of a single century. That a tiny landlocked country should become a dominant steamship builder for the rest of the world; that a country that had never seen a cotton plant should become the world’s second-largest textile producer; that a country with hardly any level terrain should come to boast the world’s most highly developed railway network; and that a country whose main export was impove...
The Grand Strategy of the Habsburg Empire
The Habsburg Empire's grand strategy for outmaneuvering and outlasting stronger rivals in a complicated geopolitical world The Empire of Habsburg Austria faced more enemies than any other European great power. Flanked on four sides by rivals, it possessed few of the advantages that explain successful empires. Yet somehow Austria endured, outlasting Ottoman sieges, Frederick the Great, and Napoleon. A. Wess Mitchell tells the story of how this cash-strapped, polyglot empire survived for centuries in Europe's most dangerous neighborhood without succumbing to the pressures of multisided warfare. He shows how the Habsburgs played the long game in geopolitics, corralling friend and foe alike into voluntarily managing the empire's lengthy frontiers and extending a benign hegemony across the turbulent lands of middle Europe. The Grand Strategy of the Habsburg Empire offers lessons on how to navigate a messy geopolitical map, stand firm without the advantage of military predominance, and prevail against multiple rivals.
The Sinews of Habsburg Power
The Sinews of Habsburg Power explores the domestic foundations of the immense growth of central European Habsburg power from the rise of a permanent standing army after the Thirty Years' War to the end of the Napoleonic wars. With a force that grew irregularly in size from around 25,000 soldiers to as many as half a million in the War of the Sixth Coalition, the Habsburg monarchy participated in shifting international constellations of rivalry from western Europe to the Near East and in some two dozen, partly overlapping armed conflicts. Raising forces of such magnitude constituted a central task of Habsburg government, one that ultimately required the cooperation of society and its elites. ...
