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Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.
This publication examines how opening sequences in films, classic and contemporary, act as hooks to draw the viewer into the film, showing frame by frame how graphics, type and animation are used to create atmosphere, set tone, and lend impact to movies. From Hitchcock and Godard to Tarantino, Luc Besson, and Tim Burton, this large format coffee table book finally illuminates this critical role designers play in filmmaking and gives credit to those that often go uncredited.
Each chapter presents a detailed background of the described method, its theoretical foundations, and its applicability to different biomedical material. Updated chapters describe either the most popular methods or those processes that have evolved the most since the past edition. Additionally, a large portion of the volume is devoted to clinical cytometry. Particular attention is paid to applications of cytometry in oncology, the most rapidly growing area. - Contains 56 extensive chapters authored by world authorities on cytometry - Covers a wide range of topics, including principles of cytometry and general methods, cell preparation, tandardization and quality assurance, cell proliferation...
During the past decade significant developments have been achieved in the field of magnetic resonance imaging (MRI), enabling MRI to enter the clinical arena of chest imaging. Standard protocols can now be implemented on up-to-date scanners, allowing MRI to be used as a first-line imaging modality for various lung diseases, including cystic fibrosis, pulmonary hypertension and even lung cancer. The diagnostic benefits stem from the ability of MRI to visualize changes in lung structure while simultaneously imaging different aspects of lung function, such as perfusion, respiratory motion, ventilation and gas exchange. On this basis, novel quantitative surrogates for lung function can be obtained. This book provides a comprehensive overview of how to use MRI for imaging of lung disease. Special emphasis is placed on benign diseases requiring regular monitoring, given that it is patients with these diseases who derive the greatest benefit from the avoidance of ionizing radiation.
The battle for the United Planets hits a fever pitch as the galactic conqueror Mongul beats some of the rulers of the galaxy to death and then heads for Earth! The only thing standing in his way? Superman! Meanwhile, back on Earth, the truth that Clark Kent is Superman continues to spiral out all over the world, and now the Daily Planet’s competition is gunning for his wife, Lois Lane!
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First Published in 2004. 'Emmanuel Levinas's thought can make us tremble' exclaims Jacques Derrida, one of the increasing number of writers in many different fields through whose works reverberate shock waves transmitted by the prophetic words of this eminent contemporary philosopher. John Llewelyn's exemplary study hears in Levinas's words an argument to the effect that is ethics is in crisis today it is because we fail to acknowledge that there is crisis in ethics from all time. After Auschwitz, he asks, dare we leave unheeded what Levinas has to say?
"Mobile Phone Ownership is considerably more ubiquitous than internet access via personal computers: more and more people around the world are carrying a tiny mobile device of some kind in their pocket or handbag. The environment in which people find and use information is changing - we are busier, we are constantly on the move and whether we are shopping, booking a holiday or looking for train times we expect instant results. What does all this mean for libraries?" "The development of networked technologies opened up huge opportunities for libraries to make their resources and services accessible to their users regardless of distance. The opportunity to deliver these to users via their mobi...
A meditation on the relationship between pop star and pop fan, this intriguing and thoroughly entertaining epistolary novel tracks a 30-year, one-way correspondence from devoted music fan Gary to rock icon David Bowie. Beginning as an angst-ridden teenager, Gary writes letters to Bowie, sharing his thoughts on everything from Ziggy Stardust and Glass Spiders to his boarding school days and adult life as a husband and father.