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TRP Channels in Health and Disease
Almost 25 years ago, the first mammalian transient receptor potential (TRP) channel was cloned and published. TRP channels now represent an extended family of 28 members fulfilling multiple roles in the living organism. Identified functions include control of body temperature, transmitter release, mineral homeostasis, chemical sensing, and survival mechanisms in a challenging environment. The TRP channel superfamily covers six families: TRPC with C for “canonical”, TRPA with A for “ankyrin”, TRPM with M for “melastatin”, TRPML with ML for “mucolipidin”, TRPP with P for “polycystin”, and TRPV with V for “vanilloid”. Over the last few years, new findings on TRP channels have confirmed their exceptional function as cellular sensors and effectors. This Special Book features a collection of 8 reviews and 7 original articles published in “Cells” summarizing the current state-of-the-art on TRP channel research, with a main focus on TRP channel activation, their physiological and pathophysiological function, and their roles as pharmacological targets for future therapeutic options.
Shades of Mao: The Posthumous Cult of the Great Leader
"Essays, poems, songs, folkloric anecdotes and photographs celebrating the myth of Mao. ... The editor supplies an insightful, and cohesing introduction". -- Reference & Research Book News "(A) highly entertaining and informative collection of translations of official, admiring, tacky, but sometimes also highly critical writings, and illustrations of objects, all featuring Mao. ... A must-have book for everybody interested in contemporary China, Mao, and his legacy now and in the future". -- China Information
Modern Chinese Theologies
It is well known that the Chinese church (and therefore Chinese theology) has been divided in the People's Republic of China into "registered" and "unregistered" churches, and that while the state-approved church offers theologies that align with the nation's socialist values, the unregistered or house churches have tended toward an evangelical theology that is now divaricating with the resurgence of denominations in China. What is less well known is that there has been a vibrant third field of Chinese theology: Sino-Christian theology, a contested, academic discourse that makes no claims to be a confessional theology. This theology, fostered by academics in secular Chinese universities, dev...
Advances in Postharvest Pathology of Fruits and Vegetables
Fruits and vegetables are an important part of a healthy diet. However, one third of fruit and vegetables are lost after harvest every year. Most losses are caused by pathogen (mostly fungi) infections, which lead to postharvest decay. In addition, some postharvest fungal pathogens can produce toxic secondary metabolites (i.e. mycotoxins) during their infecting periods. Mycotoxin contamination may cause serious food safety issues. At present, the use of synthetic fungicides is still the main means to control postharvest diseases. However, the development of resistance in fungal pathogens to fungicides and the growing public concern over the health and environmental risks associated with high levels of pesticides in fruits and vegetables have urged researchers to develop alternative methods of disease control. A deeper understanding of the infecting mechanisms of postharvest pathogens will provide great insight into developing new controlling strategies.
The Silk Road
The Silk Road is as iconic in world history as the Colossus of Rhodes or the Suez Canal. But what was it, exactly? It conjures up a hazy image of a caravan of camels laden with silk on a dusty desert track, reaching from China to Rome. The reality was different--and far more interesting--as revealed in this new history. In The Silk Road, Valerie Hansen describes the remarkable archeological finds that revolutionize our understanding of these trade routes. For centuries, key records remained hidden--sometimes deliberately buried by bureaucrats for safe keeping. But the sands of the Taklamakan Desert have revealed fascinating material, sometimes preserved by illiterate locals who recycled offi...
Postharvest Nanotechnology for Fresh Horticultural Produce
Food scarcity and insecurity is an alarming issue throughout the world. Postharvest loss due to both mechanical damage and microbial spoilage significantly influences the shelf life and hence the availability of agricultural produce. Once initiated, the microbial spoilage can make bulk quantity of a given agricultural product unacceptable for human consumption, and several methods have already been used to try to manage this. Considering the limited success of the available methods, there is increasing interest in exploring nanotechnological methods. These methods are being considered for both the development of various platforms for antimicrobial/barrier packaging applications that minimize...
