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Recent advances in the treatment of epilepsy
Epilepsy is one of the most common neurological chronic disorders characterized by unpredictable recurrent seizures, which leads to brain dysfunction, cognitive, psychological, and social disorders. Various treatment options for epilepsy are: antiepileptic drugs, surgery, neuromodulation, gene therapy and ketogenic diet. However, definitions, diagnosis and treatment of epilepsy are still challenging issues for clinicians and researchers. Antiepileptic drugs play a central and crucial role in the treatment of epilepsy patients. Brivaracetam Cannabidiol (CBD), Cenobamate, Everolimus and Fenfluramine are the five novel anticonvulsant drugs during the last 5 years. Brivaracetam anticonvulsant ef...
Traditional Medicines in Drug Discovery and Development
This comprehensive book, comprising 20 chapters contributed by respected academics in their respective fields, highlights the immense contribution of traditional medicine to the discovery and development of modern drugs. Each chapter provides in-depth details, stimulating experts to further explore the flora used in traditional medicines and inspiring younger investigators to delve into the mysterious world of secondary metabolites in their quest for novel molecules. This book is of immense value to scientists, academicians, researchers, and students alike, making it a valuable addition to personal collections and libraries.
Ethnopharmacology
Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences research on medicinal, aromatic and toxic plants with socio-cultural studies and has often been associated with the development of new drugs. The Editors of Ethnopharmacology have assembled an international team of renowned contributors to provide a critical synthesis of the substantial body of new knowledge and evidence on the subject that has emerged over the past decade. Divided into three parts, the book begins with an overview of the subject including a brief history, ethnopharmacological methods, the role of intellectual property protectio...
Postrevolutionary Iran
The 1979 revolution fundamentally altered Iran’s political landscape as a generation of inexperienced clerics who did not hail from the ranks of the upper class—and were not tainted by association with the old regime—came to power. The actions and intentions of these truculent new leaders and their lay allies caused major international concern. Meanwhile, Iran’s domestic and foreign policy and its nuclear program have loomed large in daily news coverage. Despite global consternation, however, our knowledge about Iran’s political elite remains skeletal. Nearly four decades after the clergy became the state elite par excellence, there has been no empirical study of the recruitment, c...
Chronic Inflammation and Neurodegeneration in Retinal Disease
We would like to acknowledge and thank Francesco Petrillo, Carlo Gesualdo, Chiara Bianca Maria Platania and Maria Consiglia Trottafor their support on the collection’s Editorial article.
Bioactive Compounds Against SARS-CoV-2
Coronaviruses can cause illness, severe disease, and death; for example, Middle East respiratory syndrome (MERS), severe acute respiratory syndrome (SARS), and COVID-19. Vaccine development and antiviral drugs are challenged by the propensity for viral mutations allowing these viruses to evade such therapies. There are a number of bioactive compounds from natural sources, which can exert health benefits and act as antiviral therapies such as anti-inflammation, antioxidative stress, and immune regulation. This book summarizes research on the potential efficacy and underlying mechanisms of bioactive compounds and traditional medicines against SARS-CoV-2. Key Features Summarizes the potential benefits of bioactive therapies for coronaviruses Focuses on COVID-19, but also covers MERS and SARS Provides alternatives to vaccines and other antiviral drugs whose efficacy is reduced by viral mutations Relevant for clinicians and public health officials
10 Years of Ethnopharmacology
The contributions selected for this ebook span the entire ten-year period and we have selected examples which have had a particular impact on the debates in the field. Broadly speaking, they fall into four main areas: - Overarching reviews within ethnopharmacology - Reviews of specific species or other taxa regarding their pharmacology; phytochemistry and local / traditional use - Assessments of the pharmacological evidence for specific active compounds or classes of compounds - Assessments of the safety and potential risks of herbal substances. With these themes, this eBook contributes to the debate about the evidence- base of such practices incorporating both the scientific evidence available and the local / traditional concepts associated with their use.
Role of Apoptosis in Infection
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