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As the most powerful explosion that occurs in the universe, gamma-ray bursts (GRBs) are one of the most exciting topics being studied in astrophysics. Creating more energy than the Sun does in its entire lifetime, GRBs create a blaze of light that will outshine every other object visible in the sky, enabling us to measure galaxies that are several million years old.GRBs cover various areas of astronomy and interest in them reaches a wide range of fields. Andrew Levan explores the fascinating history of these astronomical occurrences and details our current understanding of GRBs. The science behind them is rapidly moving and this book examines the knowledge that we now have as well as the questions that are continually being raised. Predominantly aimed at PhD students and researchers in the area, Gamma-Ray Bursts addresses this captivating topic and outlines the principles and initial applications of a fascinating astronomical phenomena.
Coeliac Disease and Gluten-Related Disorders provides an updated and comprehensive overview on the crucial aspects and clinical management of gluten-related disorders. It provides an overview of the scientific background, mechanisms involved, and emphasizes the translational effect of research on clinical practice. Highlighted throughout are insights into future research areas likely to have a crucial impact in the clinical management of these common conditions. The book is perfect for researchers and gastroenterologists involved in Coeliac Disease and other gluten-related disorders. - Presents both research and clinically based perspectives on the most relevant issues of gluten-related disorders - Provides a wide-ranging discussion and the most updated opinions by international experts in the field of coeliac disease and gluten-related disorders - Translates the latest research insights into practical suggestions for specialists
There has been a dramatic shift towards more open forms of innovation. Drawing on practice-based insights, together with theoretical approaches developed in innovation studies & science & technology studies, this book brings together a collection of recent work that examines key aspects of this model of innovation.
DNA replication is a fundamental part of the life cycle of all organisms. Not surprisingly many aspects of this process display profound conservation across organisms in all domains of life. The chapters in this volume outline and review the current state of knowledge on several key aspects of the DNA replication process. This is a critical process in both normal growth and development and in relation to a broad variety of pathological conditions including cancer. The reader will be provided with new insights into the initiation, regulation, and progression of DNA replication as well as a collection of thought provoking questions and summaries to direct future investigations.
For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and b...
This book tries to close the gap between immunological findings on the one hand, psychological, psychopathological, electrophysiological and neuroimaging aspetcs on the other. It deals with the issue of "cause and effect” (of immunological alternatives) in different organic and/or mental disorders, and emphasizes the necessity of considering a variety of treatment strategies. There are dynamic interactions and several important similarities between the immune system and the central nervous system, which help to lay the rational basis for "psychoimmunology”. Both systems have the capacity for memory and both play vital roles in adaptation and defence. Furthermore, in each system pathological changes can occur in the event of inappropriate responses to internal or external stimuli, leading to psychiatric as well as organic illnesses and autoimmune diseases could also arise as a consequence of dysfunction respectively maladaptation. "... this book is a good way to approach the field of psychoimmunology, and shows that scientists are very active in this domain ...” Acta Neurologica Belgica.
In a context where schools are held more and more accountable for the education they provide, data-based decision making has become increasingly important. This book brings together scholars from several countries to examine data-based decision making. Data-based decision making in this book refers to making decisions based on a broad range of evidence, such as scores on students’ assessments, classroom observations etc. This book supports policy-makers, people working with schools, researchers and school leaders and teachers in the use of data, by bringing together the current research conducted on data use across multiple countries into a single volume. Some of these studies are ‘best practice’ studies, where effective data use has led to improvements in student learning. Others provide insight into challenges in both policy and practice environments. Each of them draws on research and literature in the field.
From simple cases such as hook and latch attachments found in Velcro to articulated-wing flying vehicles, biology often has been used to inspire many creative design ideas. The scientific challenge now is to transform the paradigm into a repeatable and scalable methodology. Biologically Inspired Design explores computational techniques and tools that can help integrate the method into design practice. With an inspiring foreword from Janine Benyus, Biologically Inspired Design contains a dozen chapters written by some of the leading scholars in the transdisciplinary field of bioinspired design, such as Frank Fish, Julian Vincent and Jeannette Yen from biology, and Amaresk Chakrabarti, Satyand...