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Cell-free Circulating Dna: Purification And Analysis Techniques
Circulating cell-free DNA is poised to transform cancer diagnosis and care; however, it carries technical challenges such as low abundance, fragmentation and sensitivity to biospecimen handling. Development of clinically useful assays hinges on understanding the unique technical aspects of working with cell-free DNA as a substrate. This book provides an in-depth summary of the technical issues impacting cell-free DNA purification from blood plasma and analysis in a cancer context, including design of PCR assays, sequencing library preparation and methylation analysis. Emerging fields such as extracellular vesicles and blood nucleases are also covered, as well as basic biology and considerations pertinent to biobanking.
Making Stars
Making Stars provides multiple perspectives on the simultaneous emergence of modern forms of life writing and celebrity culture in eighteenth-century Britain. Crossing multiple genres and media, contributors reveal the complex and varied ways in which these modern ways of thinking about individual identity mutually conditioned their emergence during this formative period.
The Temporality of Taste in Eighteenth-Century British Writing
This book discusses the disruptive power of the concept of taste in the works of a number of important British writers, including poets such as Alexander Pope and Joseph Warton, philosophical historians such as David Hume and Anna Barbauld, and novelists such as Frances Burney and William Beckford.
Exile as a Continuum in Joseph Conrad’s Fiction
Joseph Conrad is famous for being an unusual, strange, and even eccentric English writer. However, despite his difference, English criticism has primarily interpreted his fiction from the perspective of the English culture. In turn, Polish criticism has portrayed Conrad as a Pole who happened to write in English. Considering Conrad’s transcultural background, neither exclusively English nor an exclusively Polish writer, this volume investigates the essential features of his expatriate writing as a form distinctly different from any writing done within a single culture. Conrad's unique contribution to English literature and sensibility stems from his ability to incorporate the complexity of...
Wildlife Review
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Virgin Whore
In Virgin Whore, Emma Maggie Solberg uncovers a surprisingly prevalent theme in late English medieval literature and culture: the celebration of the Virgin Mary’s sexuality. Although history is narrated as a progressive loss of innocence, the Madonna has grown purer with each passing century. Looking to a period before the idea of her purity and virginity had ossified, Solberg uncovers depictions and interpretations of Mary, discernible in jokes and insults, icons and rituals, prayers and revelations, allegories and typologies—and in late medieval vernacular biblical drama. More unmistakable than any cultural artifact from late medieval England, these biblical plays do not exclusively in...
Old Norse Religion in Long-Term Perspectives
Consisting of more than 70 papers written by scholars concerned with pre-Christian Norse religion, the articles discuss subjects such as archaeology, art history, historical archaeology, history, history of ideas, theological history, literature, onomastics, Scandinavian languages, and Scandinavian studies. The interdisciplinary aim of the book brings together text-based and material-based researchers to improve scholarly exchange and dialogue and provide a variety of contributions that elucidate topics such as worldview and cosmology, ritual and religious practice, myth and memory, as well as reception and present-day use of old Norse religion.
Studies in Eighteenth-Century Culture
With this well-illustrated new volume, the SECC continues its tradition of publishing innovative interdisciplinary scholarship on the interpretive edge. Essays include: Misty Anderson, Our Purpose is the Same: Whitefield, Foote, and the Theatricality of MethodismTili Boon Cuillé, La Vraisemblance du merveilleux: Operatic Aesthetics in Cazotte's Fantastic FictionSimon Dickie, Joseph Andrews and the Great Laughter Debate: The Roasting of AdamsLynn Festa, Cosmetic Differences: The Changing Faces of England and FranceBlake Gerard, All that the heart wishes: Changing Views toward Sentimentality Reflected in Visualizations of Sterne's Maria, 1773-1888Jennifer Keith, The Sins of Sensibility and th...
