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Abstract: Protein-energy malnutrition (PEM) is classified inthree basic types: kwashiorkor, marasmus and kwashiorkor marasmus. Classification is based on presence or absence of oedema and deficit in body weight. General clinical featuresof all classifications are growth failure, skin and hair changes, hepat omegaly and psychological changes. Oedema is characteristic of kwashiorkor and kwashiokor marasmus. Mortality in severe PEM is high. The most important scientific aspects, with direct bearing on treatment and prevention of PEM in children, are 1) the ecology, pathogenesis, pathology and biochemistry of PEM; 2) infection-PEM interaction; 3) treatment; 4) long-term effects on child development; 5) nutritional status assessment; 6) prevention and rehabilitation of protein-energy malnutrition.
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