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Significant progress in the science and technology of the mechanical behaviour of materials has been made in recent years. The greatest strides forward have occurred in the field of advanced materials with high performance, such as ceramics, composite materials, and intermetallic compounds. The Sixth International Conference on Mechanical Behaviour of Materials (ICM-6), taking place in Kyoto, Japan, 29 July - 2 August 1991 addressed these issues. In commemorating the fortieth anniversary of the Japan Society of Materials Science, organised by the Foundation for Advancement of International Science and supported by the Science Council of Japan, the information provided in these proceedings reflects the international nature of the meeting. It provides a valuable account of recent developments and problems in the field of mechanical behaviour of materials.
Chronic hepatitis C is a major worldwide health problem affecting more than 170 million people. Chronic infections lead to cirrhosis and liver failure or hepatocellular cancer in many instances. This volume includes comprehensive reviews that cover much of the vast literature that has appeared since the identification of the hepatitis C virus RNA genome. It will be an invaluable collection for anyone wanting an up-to-date picture of HCV transmission, molecular virology, immune response, cellular/molecular pathogenesis, and possible avenues for developing effective new therapeutics and vaccines.
Every cell of the body is dependent on calcium to function. Calcium is found in teeth and bones, and calcium signalling is necessary for the movement of muscles and for the action of the heart and the intestines as well as blood coagulation. Calcium in Living Cells will update classic techniques in detecting microscopic levels of calcium ions (Ca2+) in living cells, as well as address new techniques in the field of calcium detection and calcium signaling. Such detection and measurement of intracellular calcium is important to researchers studying the heart, musculoskeletal, gastrointestinal, and immune systems, whose findings will aid in the advancement of drug and genomic therapies to treat...
Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field.
Non-conventional synthetic methods may provide new and green methods for the preparation of bioactive heterocycles. These methods, such as microwave and ultrasound assisted synthesis, biocatalysis, photochemistry and electrosynthesis use less energy and may produce less waste to get the desired products when compared to traditional methods. This book explores the use of these methods when synthesizing various biologically relevant heterocyclic scaffolds. THE SERIES: GREEN BIOACTIVE HETEROCYCLES Heterocycles are a widely utilized group of molecules as they often contain bioactivity that is useful in drug development, agriculture, and other applications. However, their synthesis remains challenging with diffi cult to control functional groups. With a greater focus on sustainable synthesis practices, there is a need to develop greener synthetic methods for the synthesis of structurally diverse bioactive heterocyclic scaffolds. This series aims to do so, by collecting developments into common themes.
The discovery of the human T cell leukemia virus type I in the late 1970s heralded a new era in retrovirology. For the first time, it was demonstrated that a retrovirus could play a role in the development of a human disease, in this case adult T cell leukemia (ATL). Several years later, the acquired immunodeficiency syndrome (AIDS) epidemic began, and it was dem- strated that a retrovirus, originally designated the human T cell lymp- tropic virus type 3, was the causal agent of this syndrome. This virus, later named the human immunodeficiency virus type 1 (HIV-1), has since been extensively studied in terms of its pathogenesis as well as its ability to elicit immune responses. In that time,...
The odontode system, which encompasses teeth and other dentine-based structures, is ancient. Odontodes are present in the oldest vertebrate fossils, dating back 500 million years, and still play an important role in the anatomy and function of living jawed vertebrates. Fossils preserve odontode tissues with remarkable nanoscale fidelity, allowing the evolution and diversification of the odontode system to be studied in deep time as well as across the diversity of living vertebrates. This synthetic volume presents an overview of odontode research by internationally leading researchers from different fields of biology.. Key Features Summarizes classic and cutting-edge research devoted to the development and evolution Focuses on the cellular aspects of odontogenesis Documents the structural and functional diversity of odontode tissues Describes the patterning mechanisms of dentitions in various vertebrate groups Provides a thorough index for students