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A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field. The book...
The Junipers of the World contains a synthesis of data on evolution by examining: Geographic Variation: Pan-Arctic variation in Juniperus communis, etc. Speciation in sections of the genus: Species concepts, Speciation in Juniperus section Juniperus, etc. In addition, Keys to Juniperus are provided by region: Eastern Hemisphere, Europe (including Azores, Canary Islands, Asia Minor and Africa), Central Asia (Turkmenistan to western Himalayas), China, Far East (Japan, Korea, Sakhalin Island, Taiwan), Western Hemisphere, Continental North America, United States and Canada, Mexico and Guatemala, and the Caribbean. Also included are Species' Descriptions, Distribution Maps and Plant Photos, and c...
This monograph outlines the basic theory of optical parametric processes and presents discussions on materials and practical device considerations. It emphasizes on optical parametric oscillators and mainly focuses on the three-photon parametric process.
Gastric motility disorders remain a complex clinical challenge, and inflict a substantial burden of cost and suffering on society. Gastric contractions are coordinated by an underlying electrical activity, and gastric dysrhythmias are implicated in the pathophysiology of several motility disorders. However, the significance of dysrhythmias remains uncertain, and there are few elective therapies, because current tools to investigate dysrhythmias have low reliability owing to their lack of spatial resolution. This thesis aimed to develop an improved foundation for the investigation and management of gastric dysrhythmia, by advancing and translating high-resolution (HR; multi-electrode) spatiot...
Nonlinear Optical Crystals contains the most complete and up-to-date reference material on properties of nonlinear optical crystals including: Traditional and specific applications The mathematical formulas necessary for the calculation of the frequency conversion process A survey of 63 nonlinear optical crystals containing more than 1500 different references with full titles Recent applications of common and novel nonlinear materials, including quasi-phase matching Special consideration for periodically-poled and self-frequency-doubling materials Significant amount of crystallophysical, thermophysical, spectroscopic, electro-optic and magneto-optic information
At the ICAB 2014, researchers from around the world will gather to discuss the latest scientific research, findings and technologies concerning Microbial Genetics and Breeding, Optimization and Control of Biological Processes, Biological Separation and Biological Purification, and Advances in Biotechnology. This conference will provide a platform for academic exchange on the application of biotechnology between domestic and international universities, research institutes, corporate experts and scholars. The participants will focus on the international development and future trends. The event will lay a solid foundation for addressing key technical challenges in various areas of applied biotechnology, providing opportunities to promote the development and expansion of the biotechnology industry.
This volume provides an up-to-date coverage of the theory and applications of ordered random variables and their functions. Furthermore, it develops the distribution theory of OS systematically. Applications include procedures for the treatment of outliers and other data analysis techniques. Even when chapter and section headings are the same as in OSII, there are appreciable changes, mostly additions, with some obvious deletions. Parts of old Ch. 7, for example, are prime candidates for omission. Appendices are designed to help collate tables, computer algorithms, and software, as well as to compile related monographs on the subject matter. Extensive exercise sets will continue, many of them replaced by newer ones.
This widely-acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964. Almost all branches of chemistry and material science now interface with organometallic chemistry--the study of compounds containing carbon-metal bonds. Organometallic compounds range from species which are so reactive that they only have a transient existence at ambient temperatures to species which are thermally very stable. Organometallics are used extensively in the synthesis of useful compounds on both large and small scales. Industrial processes involving plastics, polymers, electronic material...
Chinese business firms and their networks of personal and business relationships, are becoming increasingly important players in the global economy. This book examines the global and regional operations of Chinese business firms and considers their implications for the management and organisation of these firms, aided by specific case studies. Written by leading researchers in this field, The Globalisation of Chinese Business Firms is a valuable and timely contribution to the study of Asian business systems.
The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.