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Practical Work in School Science
Practical work has been part of science education for just over 100 years and is accepted as an essential and exciting part of understanding this discipline. Although it can be costly and sometimes messy, it simply has to be done if students and teachers are to progress in their understanding. Schools and universities invest millions of pounds in it and the National Curriculum reveres it - but what exactly is going on in classrooms around the country and how are the leading practitioners moving with the times? This book attempts to reflect on the value and purpose of practical work as part of the scientific curriculum. Why are practical exercises so necessary and what do they contribute to t...
CAR T-Cell, An Issue of Hematology/Oncology Clinics of North America, E-Book
In this issue of Hematology/Oncology Clinics, guest editors Drs. Caron A. Jacobson and Parth S. Shah bring their considerable expertise to the topic of CAR T-Cell Therapy. Top experts in the field discuss the multiple ways CAR T-cell therapy can be used to help fight a variety of cancers, such as diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, mantle cell lymphoma, multiple myeloma, and B-cell acute lymphoblastic leukemia (ALL). - Contains 12 practice-oriented topics including CAR T-cells in aggressive B-cell lymphomas; CAR T-cells in multiple myeloma; CAR T-cells in AML; mechanisms of resistance of CAR T-cell therapy; the role of CAR T-cell therapy in the era of bispecific antibodies; and more. - Provides in-depth clinical reviews on CAR T-cell therapy, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Marsupial Biology
Marsupial Biology developed from contributions commissioned from those attending an international symposium held in honour of Hugh Tyndale Biscoe, Australia's most celebrated marsupial biology authority and co-author of the previous leading marsupial biology text published more than 15 years ago. The book does not comprise papers of narrow focus read at the symposium, but chapters reviewing the knowledge in each key area, written to a book format. It has been tightly edited to ensure a great degree of harmony and is suitable as a comprehensive reference text for graduate and undergraduate students.
A Handbook of Transcription Factors
Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.
Reproductive Biology of South American Vertebrates
South America is one of the few areas of the world that includes vast areas of as yet undisturbed natural habitats. These areas are home to as many as half the world's species of plants and animals. Many of the animals inhabit ing these areas are of direct and immediate economic importance, while others are of unknown potential value. With economic development of these areas, there is a coincident disruption of natural habitats that have a direct impact on the reproductive capabilities of the affected species. Re production is central to the survival of all species and, regardless of the environmental stresses imposed on them, scientific attention must be fo cused on reproductive biology as ...
