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Molecular Biology of Cancer
  • Language: en
  • Pages: 365

Molecular Biology of Cancer

Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents.

Molecular Biology of Cancer
  • Language: en
  • Pages: 471

Molecular Biology of Cancer

Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents

Why Millions Survive Cancer
  • Language: en
  • Pages: 242

Why Millions Survive Cancer

  • Type: Book
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  • Published: 2011-07-27
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  • Publisher: OUP Oxford

The enormous recent progress in fighting cancer, and the science behind it, is revealed fully for the first time in this book. The disease affects one in three over a lifetime but today more and more people are surviving as a result of the extraordinary and little known advances of science and medicine. Using scientific evidence from world cancer experts, Lauren Pecorino helps us understand the biology of cancer, the recent trends in cancer progress, and the rationale behind new cancer treatments. With recommendations about lifestyle choices that can help reduce some of the risks of getting cancer, Pecorino looks to the future in our battle with this disease.

Cloning Wild Life
  • Language: en
  • Pages: 260

Cloning Wild Life

  • Type: Book
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  • Published: 2013-09-02
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  • Publisher: NYU Press

The natural world is marked by an ever-increasing loss of varied habitats, a growing number of species extinctions, and a full range of new kinds of dilemmas posed by global warming. At the same time, humans are also working to actively shape this natural world through contemporary bioscience and biotechnology. In Cloning Wild Life, Carrie Friese posits that cloned endangered animals in zoos sit at the apex of these two trends, as humans seek a scientific solution to environmental crisis. Often fraught with controversy, cloning technologies, Friese argues, significantly affect our conceptualizations of and engagements with wildlife and nature. By studying animals at different locations, Frie...

Hyaluronan in Cancer Biology
  • Language: en
  • Pages: 467

Hyaluronan in Cancer Biology

Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer a...

Principles of Cancer Biology
  • Language: en
  • Pages: 320

Principles of Cancer Biology

  • Type: Book
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  • Published: 2013-11-01
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  • Publisher: Unknown

Principles of Cancer Biology, is an engaging book focused on providing students with a big picture view of cancer. Author Lewis Kleinsmith has written an instructional text focusing on key concepts for both students and a general audience. For those instructors who wish to delve into particular aspects of cancer biology in greater depth, each chapter contains a list of suggested readings that expand the detail as needed. The text also emphasizes the scientific evidence that underlies cancer biology, and teaches students to think critically about this evidence- as there are constantly new breakthroughs and reports in this field. For students who need the review, there are brief reviews of several topics related to DNA replication and repair, cell division, cell signaling, and inheritance patterns in chapters where these subjects are relevant. By including these reviews, the text is both accessible and engaging to a broad audience of readers who are studying cancer biology for the first time, as well as an interested general audience.

The Truth in Small Doses
  • Language: en
  • Pages: 513

The Truth in Small Doses

A decade ago Leaf, a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public's immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress-- brilliant young scientists-- are now abandoning the search for a cure.

MicroRNAs in Solid Cancer
  • Language: en

MicroRNAs in Solid Cancer

MiRNA is an extremely fast growing field, and miRNA knowledge is now believed to be a pivotal element of cancer biology. It is already evident that the discovery of miRNA has created a paradigm shift in post-genomics biology, not only for scientists accustomed to traditional central dogma of molecular biology but also for researchers studying human diseases and accustomed to traditional genetics approach of studying one gene at the time. This book provides an introduction to the basic principles of miRNA biology, overview of miRNA significance in the hallmarks of cancer, experimental techniques used in miRNA research, and in special part - miRNAs importance in wide range of solid cancers with a special focus on its potential usage in molecular pathology, predictive oncology or as a novel therapeutic targets.

Molecular Biology
  • Language: en
  • Pages: 945

Molecular Biology

The biological world operates on a multitude of scales - from molecules to tissues to organisms to ecosystems. Throughout these myriad levels runs a common thread: the communication and onward passage of information, from cell to cell, from organism to organism and ultimately, from generation to generation. But how does this information come alive to govern the processes that constitute life? The answer lies in the molecular components that cooperate through a series of carefully-regulated processes to bring the information in our genome to life. These components and processes lie at the heart of one of the most fascinating subjects to engage the minds of scientists today: molecular biology....

Human Universe
  • Language: en
  • Pages: 352

Human Universe

Top ten Sunday Times Bestseller ‘Engaging, ambitious and creative’ Guardian Where are we? Are we alone? Who are we? Why are we here? What is our future?