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Pour les Lumières
Réunit quatre textes publiés au cours des dernières années par cet historien américain des Lumières. Plaidoyer fervent des Lumières, affirmation des positions méthodologiques du chercheur dans son domaine, recherches spécifiques sur l'encyclopédisme et le commerce du livre au XVIIIe siècle.
A Taste for Comfort and Status
The Lamothes were an ordinary family in eighteenth-century Bordeaux. Well-to-do and well respected by their neighbors, they were local notables whose private and public lives suggest the importance of family, kin, and friendship networks, professional activities and cultural interests, as well as a desire to serve the public good. In this portrait of the Lamothes, Christine Adams explores the development of middle-class identity among urban professionals and reconsiders the role of this social group in the coming French Revolution. The most striking feature of this family history is that it is based on more than three hundred personal letters that circulated among the Lamothes&—parents and...
Immune Checkpoint Biology in Health and Disease
Immune Checkpoint Biology in Health and Disease, Volume 382 provides in-depth reviews on the latest progress concerning research on immune-checkpoint biology and its immunotherapeutic implications, especially in cancer. Topics connected to immune-checkpoint biology covered in this volume include Novel technologies for applying immune checkpoint blockers, Next-generation deconvolution of transcriptomic data to investigate the tumor microenvironment, Immune checkpoints targeting dendritic cells for antibody-based modulation in cancer, Immune checkpoint biology in health & disease: Immune checkpoint biology and autoimmunity in cancer patients, and much more. Other sections cover Recent advancem...
Cancer Therapy with Radiolabeled Antibodies
Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading experts examine the problems and prospects of RAIT from radiation, immunological, chemical, physical, physiological, and clinical perspectives with both overviews and original research. Discussions cover the up-to-date clinical results in the RAIT of ovarian, breast, colorectal, and brain cancers, as well as the current status of RAIT in the management of B cell lymphomas. Radiobiology, dosimetry, radiochemistry, targeting biology in experimental models, clinical experiences in hematopoietic and solid tumors, and new approaches to improve cancer radioimmunotherapy are also discussed. In addition, new dosimetry concepts, new labeling methods, new concepts of antibody pharmacokinetics, and new methods to enhance selective cancer radioimmunotherapy are included.
