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A Taste for Comfort and Status
The Lamothes were an ordinary family in eighteenth-century Bordeaux. Well-to-do and well respected by their neighbors, they were local notables whose private and public lives suggest the importance of family, kin, and friendship networks, professional activities and cultural interests, as well as a desire to serve the public good. In this portrait of the Lamothes, Christine Adams explores the development of middle-class identity among urban professionals and reconsiders the role of this social group in the coming French Revolution. The most striking feature of this family history is that it is based on more than three hundred personal letters that circulated among the Lamothes&—parents and...
Handbook of Targeted Delivery of Imaging Agents
This is the first time detailed and updated information on the targeted delivery of imaging agents has been collected into a single handbook. This comprehensive volume presents the scientific background together with the latest experimental and clinical data in this fast-growing area. The Handbook of Targeted Delivery of Imaging Agents meets the requirements of the broadest audience including researchers, practitioners, and students. The basic principles of targeted delivery of imaging are presented and discussed together with various imaging agents and different imaging modalities such as gamma-imaging, MR-imaging, and CT, PET, and SPECT imaging. The book consists of eight parts and 39 chap...
Pour les Lumières
Réunit quatre textes publiés au cours des dernières années par cet historien américain des Lumières. Plaidoyer fervent des Lumières, affirmation des positions méthodologiques du chercheur dans son domaine, recherches spécifiques sur l'encyclopédisme et le commerce du livre au XVIIIe siècle.
Tumor Targeting in Cancer Therapy
This volume introduces the principles and techniques of tumor targeting and critically surveys their applications from laboratory to bedside. By concisely synthesizing the many technical details, the authors illuminate this innovative technique, ranging from the fundamentals of drug targeting and in vivo and in vitro experimentation, to such emerging therapeutic uses as radioimmunotherapy, radioimmunodetection, therapy with cytotoxic antibodies, immunotoxins, enzyme prodrug immunotherapy, and immunotherapeutics with fusion proteins.
Cancer Therapy with Radiolabeled Antibodies
Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading experts examine the problems and prospects of RAIT from radiation, immunological, chemical, physical, physiological, and clinical perspectives with both overviews and original research. Discussions cover the up-to-date clinical results in the RAIT of ovarian, breast, colorectal, and brain cancers, as well as the current status of RAIT in the management of B cell lymphomas. Radiobiology, dosimetry, radiochemistry, targeting biology in experimental models, clinical experiences in hematopoietic and solid tumors, and new approaches to improve cancer radioimmunotherapy are also discussed. In addition, new dosimetry concepts, new labeling methods, new concepts of antibody pharmacokinetics, and new methods to enhance selective cancer radioimmunotherapy are included.
