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Small towns are places where everyone knows each other’s names—and each other’s business, despite it being none of their own. Yet, folks in small towns never seem to want to talk about mental health. Rural living can be isolating with hours spent on the farm caring for the land, animals, the home, and everyone else first before yourself. Women especially know this struggle all too well. Author Lewellyn Melnyk has experienced this her whole life, suffering from depression in her early teens that left her with what felt like only one option: to take her own life. Rooted: How I Stay Small Town Strong When Life Gets Hard and How You Can Too: A Guide to Finding Joy, Learning from Struggle, ...
Progress in Cell Cycle Research is a new annual series designed to be the source for up-to-date research on this rapidly expanding field. Review articles by international experts examine various aspects of cell division regulation from fundamental perspectives to potential medical applications. Researchers as well as advanced undergraduate and graduate students in cell biology, biochemistry, and molecular biology will benefit from this series.
This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting the importance of kinesins, summarising current knowledge and how they are shown to be crucial for mitosis. Chapters go on to explore how this family of proteins are emerging as a novel target for chemotherapeutic intervention and drug development. Readers will learn how kinesins travel along microtubules to fulfill their many roles in intracellular transport or cell division. Several compounds that inhibit two mitotic kinesins (called Eg5 and CENP-E) have e...
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Published in cooperation with the Dr. Daly Project Association Bernard Daly escaped the Irish Famine and with his family emigrated to America, where he became the town doctor in Lakeview, Oregon, and then a state legislator, Oregon Agricultural College regent, county judge, rancher, and banker. When he died in 1920, his estate, valued at about a million dollars, established a college scholarship for the youth of Lake County. Daly's scholarship fund would ensure that most of the youth of tiny, remote Lake County could attend college. Drawing on more than a hundred personal interviews, an extensive web-based survey, and archival materials, this book tells the story of Daly's life, the scholarship fund, and its impact on the recipients, who went on to remarkable careers and lives. At a time when almost no one went to college, Daly created a "college for all" possibility in a remote corner of America. The impact of the Daly Fund, one of America's oldest continuously operating place-based scholarship, offers unique insights into the benefits of higher education and how it might best be supported - questions that we are struggling with today.
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