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Women in Neuroanatomy
We are delighted to present the inaugural Frontiers in Neuroscience 'Women in Neuroanatomy' article collection. At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.
Cognitive deficits in schizophrenia and other neuropsychiatric disorders: Convergence of preclinical and clinical evidence
Neuropsychiatric diseases, such as schizophrenia, Alzheimer's disease, and etc., represent a serious medical and socioeconomic problems. These diseases are often accompanied by impairments of cognitive function, e.g., abstract thinking, decision-making, attention, and several types of memory. Such deficits significantly disrupt quality of life and daily functioning of patients. Cognitive deficits in neuropsychiatric diseases are associated with alterations of brain morphology and function, and are often resistant to therapeutic interventions. In schizophrenia and related disorders, cognitive deficits are also defined as endophenotypes, i.e. measurable phenotypes linking these disaeses with d...
Cajal's Neuronal Forest
This collection contains hundreds of beautiful rarely-seen-before figures produced throughout the nineteenth century and the beginning of the twentieth century by famed father-of-modern-neuroscience Santiago Ramón y Cajal (1852-1934) and his contemporaries. Cajal was captivated by the beautiful shapes of the cells of the nervous system. He and his fellow scientists saw neurons as trees and glial cells as bushes. Given their high density and arrangement, neurons and glial resembled a thick forest, a seemingly impenetrable terrain of interacting cells mediating cognition and behavior.
Neuroanatomy for the XXIst Century
An explosion of new techniques with vastly improved visualization and sensitivity is leading a veritable revolution in modern neuroanatomy. Basic questions related to cell types, input localization, and connectivity are being re-visited and tackled with significantly more accurate and higher resolution experimental approaches. A major goal of this e-Book is thus to highlight in one place the impressive range of available techniques, even as these are fast becoming routine. This is not meant as a technical review, however, but rather will project the technical explosion as indicative of a field now in a vibrant state of renewal. Thus, contributions will be mainly research articles using the n...
Neurostereology
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The Cortex and the Critical Point
How the cerebral cortex operates near a critical phase transition point for optimum performance. Individual neurons have limited computational powers, but when they work together, it is almost like magic. Firing synchronously and then breaking off to improvise by themselves, they can be paradoxically both independent and interdependent. This happens near the critical point: when neurons are poised between a phase where activity is damped and a phase where it is amplified, where information processing is optimized, and complex emergent activity patterns arise. The claim that neurons in the cortex work best when they operate near the critical point is known as the criticality hypothesis. In th...
Neuroanatomy of Human Brain Development
The human brain is extraordinary complex and yet its origin is a simple tubular structure. Rapid and dramatic structural growth takes place during the fetal and perinatal period. By the time of birth, a repertoire of major cortical, subcortical and white matter structures resembling the adult pattern has emerged, however there are continued maturational changes of the gray matter and white matter throughout childhood and adolescence and into adulthood. The maturation of neuronal structures provides the neuroanatomical basis for the acquisition and refinement of cognitive functions during postnatal development. Histological imaging has been traditionally dominant in understanding neuroanatomy...
The First Outstanding 50 Years of “Università Politecnica delle Marche”
The book describes the significant multidisciplinary research findings at the Università Politecnica delle Marche and the expected future advances. It addresses some of the most dramatic challenges posed by today’s fast-growing, global society and the changes it has caused. It also discusses solutions to improve the wellbeing of human beings. The book covers the main research achievements in the various disciplines of the life sciences, and includes chapters that highlight mechanisms relevant to all aspects of human diseases, the molecular, cellular, and functional basis of therapy, and its translation into the management of people’s health needs. It also describes research on tradition...
Interactive World, Interactive God
Since the dawn of science, ideas about the relation between science and religion have always depended on what else is going on in a society. During the twentieth century, daily life changed dramatically. Technology revolutionized transportation, agriculture, communications, and housework. People came to rely on scientific predictability in their technology. Many wondered whether God's supposed actions were consistent with scientific knowledge. The twenty-first century is bringing new scientific research capabilities. They are revealing that scientific results are not totally predictable after all. Certain types of interaction lead to outcomes that are unpredictable, in principle. These in tu...
Designing Intelligent Healthcare Systems, Products, and Services Using Disruptive Technologies and Health Informatics
Disruptive technologies are gaining importance in healthcare systems and health informatics. By discussing computational intelligence, IoT, blockchain, cloud and big data analytics, this book provides support to researchers and other stakeholders involved in designing intelligent systems used in healthcare, its products, and its services. This book offers both theoretical and practical application-based chapters and presents novel technical studies on designing intelligent healthcare systems, products, and services. It offers conceptual and visionary content comprising hypothetical and speculative scenarios and will also include recently developed disruptive holistic techniques in healthcare...
