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This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.
Wenn auch marginalisiert, stellt literarische Mehrsprachigkeit keineswegs ein randständiges Phänomen der Literatur dar. Vielmehr lässt sie sich in verschiedensten Epochen aufspüren und sie manifestiert sich in vielfältigen sprachlich-ästhetischen Formen. Dabei eröffnen Sprachmischungen, Hybridisierungen und Neuformierungen ästhetische Zwischenräume sowie erweiterte Möglichkeiten der Deutung und Interpretation. Im Fokus dieses Bandes stehen Ästhetiken, Entwicklungen, Formen und Funktionen literarischer Mehrsprachigkeit in Geschichte und Gegenwart, die auch hinsichtlich ihrer didaktischen Potenziale untersucht werden. Neben literaturwissenschaftlichen Perspektiven erörtern die Beiträge insbesondere literaturdidaktische Ansätze, die literarische Mehrsprachigkeit in poetischen Texten ins Zentrum stellen. Dabei werden verschiedene Formen des Inter-, Trans- oder Heterolingualen didaktisch reflektiert und/oder aus einer dominanzsprachkritischen Perspektive für den Literaturunterricht fruchtbar gemacht.
Wie kaum ein anderer Schriftsteller fühlte sich Paul Celan an das Deutsche gebunden. Doch wie selten ein Dichter vor ihm integrierte er eine Vielzahl anderer Sprachen in seine literarische Praxis. Die Bedeutung dieses Schreibens ,zwischen' den Sprachen lässt sich aus seiner Biographie, seinem Werk und seiner Poetik herleiten und anhand vieler Textbeispiele veranschaulichen. Auf verschiedenen Ebenen und in unterschiedlichen Formen sind ein Dutzend Sprachen in Phänomene des Sprachwechsels, der Sprachmischung und der Sprachreflexion involviert. In dieser Studie wird erstmals der Versuch unternommen, Paul Celans Mehrsprachigkeit differenziert in ihrer ganzen Breite und Tiefe darzustellen. Dabei wird sichtbar, dass die translinguale Schreibpraxis des Dichters den Kristallisationspunkt seines distanziert-kritischen, Verhältnisses zur deutschen Muttersprache darstellt. Als Trägersprache der Judenvernichtung wird das Deutsche seiner Lyrik multilingual ,anreichert', verfremdet und dekonstruiert, wodurch eine Poetik der ,Wortöffnungen' sichtbar wird.
From the critically acclaimed author of Amina’s Voice comes a new story inspired by Louisa May Alcott’s beloved classic, Little Women, featuring four sisters from a modern American Muslim family living in Georgia. When Jameela Mirza is picked to be feature editor of her middle school newspaper, she’s one step closer to being an award-winning journalist like her late grandfather. The problem is her editor-in-chief keeps shooting down her article ideas. Jameela’s assigned to write about the new boy in school, who has a cool British accent but doesn’t share much, and wonders how she’ll make his story gripping enough to enter into a national media contest. Jameela, along with her three sisters, is devastated when their father needs to take a job overseas, away from their cozy Georgia home for six months. Missing him makes Jameela determined to write an epic article—one to make her dad extra proud. But when her younger sister gets seriously ill, Jameela’s world turns upside down. And as her hunger for fame looks like it might cost her a blossoming friendship, Jameela questions what matters most, and whether she’s cut out to be a journalist at all...
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The southwestern deserts stretch from southeastern California to west Texas and then south to central Mexico. The landscape of this region is known as basin and range topography featuring to “sky islands” of forest rising from the desert lowlands which creates a uniquely diverse ecology. The region is further complicated by an international border, where governments have caused difficulties for many animal populations. This book puts a spotlight on individual research projects which are specific examples of work being done in the area and when they are all brought together, to shed a general light of understanding the biological and cultural resources of this vast region so that those same resources can be managed as effectively and efficiently as possible. The intent is to show that collaborative efforts among federal, state agency, university, and private sector researchers working with land managers, provides better science and better management than when scientists and land managers work independently.
The multidisciplinary science of chemical proteomics studies how small molecules of synthetic or natural origin bind to proteins and modulate their function. In Chemical Proteomics: Methods and Protocols, expert researchers in the field provide key techniques to investigate chemical proteomics focusing on analytical strategies, how probes are generated, techniques for the discovery of small molecule targets and the probing of target function, and small molecule ligand and drug discovery. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Chemical Proteomics : Methods and Protocols seeks to provide methodologies that will contribute to a wider application of chemical proteomics methods in biochemical and cell biological laboratories.